Retina

A case study involving a patient with a macular pucker with a partial posterior vitreous detachment

A novel nanosecond laser therapy has stopped the progression of age-related macular degeneration (AMD) and resulted in resolution of drusen and improved visual function in patients with early-stage high-risk AMD.

A specific diode laser is the latest technology to perform several different laser procedures in the ophthalmic practice. Its multi-use capabilities for glaucoma and retinal disease make it a strong choice for the office setting.

Combined genomic and proteomic biomarkers are seemingly the most effective method for predicting progression.

A report on the status of the 5-year-old ongoing MacTel Project, which is slowly answering questions surrounding the disease.

The efficacy and safety of two doses of a fluocinolone acetonide intravitreal insert for the treatment of DME were investigated in two sham-controlled phase III studies

Results of a recent clinical study provide promising evidence of the value of ultra-widefield fundus autofluorescence (FAF) imaging in the evaluation of age-related macular degernation (AMD)

A rare case of bilateral pigmented atrophic changes in the macular region associated with topiramate treatment for chorioathetosis in a young female is reported.

Results from preclinical testing including a formal Good Laboratory Practice toxicity study, support the safety of a gene transfer agent, AAV2-sFLT01, when administered intravitreally. A phase I safety and tolerability study of this agent is currently underway.

Study shows little difference between these forms of endotamponade in patients with PVR

New performance assessments suggest retinal prothesis augments native vision

Positive pooled results from the MIVI-TRUST phase III programme are a sign that a microplasmin one-off injection will be a real alternative to surgery

Doctors may be the first clinicians to detect the presence of a sexually transmitted disease (STD) when discovering ocular manifestations associated with STDs. However, since many of the ocular manifestations of STDs can be present with other conditions, further work is required.

Dr Michael Trese explains how a web-based disease management imaging system could enhance screening for retinopathy of prematurity through acquisition and reading of weekly digital retinal images, hospital support and more opportunities for parental involvement.

Investigational agent shown to be superior to placebo in two historic multicentre studies

Doctors place focus on delivery of care

Retinal surgeons refine technology, instrumentation to optimize safety and efficacy

VisionCare&#;s implantable telescope for end-stage AMD has finally been given FDA approval. The device, discussed in depth in Ophthalmology Times Europe July 2007, was given CE approval three years ago but has subsequently been undergoing rigorous clinical trials in the United States.

For neovascular AMD sufferers, this combination therapy may offer an alternative to continual anti-VEGF injections

Clinician-scientist also trained ophthalmic leaders

Optos's scanning laser ophthalmoscope devices, the P200, P200C and P200MA have been used in a number of clinical studies, aimed at evaluating the effectiveness of an optomap ultra-widefield retinal scan in detecting potentially harmful lesions in the retina.

Exploring management, follow-up and researching into pharmaceutical approaches to treatment

The Diabetic Retinopathy Clinical Research Network (DRCR.net) study, published in Ophthalmology online has shown that ranibizumab (Lucentis) injections, in combination with laser treatment has produced better vision results than in patients treated by laser alone for diabetic macular oedema (DME).

Oraya Therapeutics has been granted the CE mark for its IRay system, which its researchers say can deliver low-energy X-rays to treat wet AMD.

Evidence suggests that supplementation with lutein, zeaxanthin and fish oils has a protective effect