Weekly review in ophthalmology: 14 May - 20 May

An end-of-week review of what happened in ophthalmology from 14 May to 20 May.

A new treatment paradigm with ab-interno canaloplasty for POAG

With minimally invasive surgery procedures becoming increasingly popular in glaucoma management, canaloplasty using an ab-interno surgical technique offers enhanced natural aqueous outflow in open-angle glaucoma.

Nanoemulsion formulation enhances IOP reduction, study finds

In research sponsored by Skye Bioscience Inc., investigators at the University of Mississippi have demonstrated stronger and longer-lasting reduction of intraocular pressure when a proprietary molecule, SBI-100, is formulated as a nanoemulsion containing the mucoadhesive agent Carbopol 940.

Chronic IOP elevation affects cerebrovascular reactivity in murine visual cortex, linked to widespread brain changes

May 02, 2022

Investigators from the New York University Grossman School of Medicine presented data at the ARVO 2022 annual meeting that concluded mapping of the relative cerebrovascular reactivity in the murine brain showed widespread brain changes resulting from the chronic IOP elevation and demonstrates vascular involvement in glaucoma both within and beyond the primary visual pathways.

Japanese investigators identify gene required for survival of retinal ganglion cells

March 27, 2022

A team of investigators at the Okinawa Institute of Science and Technology Graduate University in Japan have identified a gene necessary for the survival of retinal ganglion cells—a class of neurons located in the retina that are critical for vision.