Inflammation & Infection

Autoimmune uveitis targeted by AAV gene therapy

Investigators have found that 1 intravitreal injection of an adeno-associated virus encoding an immunosuppressive transgene, either HLA-G or eqIL-10, reduced the clinical and histologic inflammation in a well-established model of autoimmune uveitis.

U.S. FDA grants orphan drug designation to ADX-2191 from Aldeyra Therapeutics

The U.S. FDA granted orphan drug designation to ADX-2191, methotrexate for intravitreal injection, as treatment for retinitis pigmentosa.

Pearls for ocular surgical success in patients with chronic uveitis

While operating on a patient with chronic uveitis presents some challenges, there are a few pearls that may increase success.

Considering antibiotics use in postoperative endophthalmitis

June 01, 2021

Whilst endophthalmitis following cataract surgery can lead to serious vision outcomes, there are ways of minimising the risk of it occurring whilst also being mindful of the need to prescribe antibiotics in a way that does not worsen antimicrobial resistance.

Looking at 10 years of dry eye disease flares

May 06, 2021

Dr Christopher Starr discusses key points from his virtual ARVO 2021 presentation regarding dry eye disease flares, including a rapid readout assessment of 10 years' worth of world literature to analyze studies in which the inflammatory disease's condition are categorized.

Navigating COVID-19 with ophthalmic patients in the hospital setting

February 22, 2021

Experience at one ophthalmic practice in Bulgaria demonstrates that new operating procedures, technologies and good management can enable clinics to remain open and operate safely during the COVID-19 pandemic. Ophthalmic training and education should continue to be a priority.