Inflammation & Infection

Weekly review in ophthalmology: 14 May - 20 May

An end-of-week review of what happened in ophthalmology from 14 May to 20 May.

Strategic alliance combines resources to develop treatment option for dry eye syndrome

BRIM Biotechnology Inc. has entered into a new strategic partnership with Ora Inc. for the late-stage clinical development of lead drug candidate BRM421 for dry eye syndrome (DES).

Acute and chronic care required for eye with SJS/TEN ocular involvement

Patients are at risk for developing severe dry eye and ocular surface disease.

Positive topline data from Saturn-2 Phase 3 trial encourages Tarsus to file NDA in 2022

May 08, 2022

TP-03 met the primary and all secondary endpoints, effectively resolved Demodex blepharitis and was well-tolerated with no serious treatment-related adverse events. 56% of patients on TP-03 achieved the primary endpoint of complete collarette cure.

Predicting metastasis with novel prognostic liquid biopsy for uveal melanoma

May 04, 2022

Investigators from the Karolinska Institutet and St. Erik Eye Hospital, Stockholm, Sweden, reported that they have developed a prognostic test, referred to as serUM, that they believe is a strong predictor of metastasis of uveal melanoma.

Sealing masks to skin with tape may decrease risk of ocular surface damage during the COVID-19 pandemic

May 02, 2022

During a presentation at the Association for Research in Vision and Ophthalmology’s 2022 annual meeting, Dr Yuichi Hori and colleagues found that taping the top border of a surgical mask to a clinicians’ skin reduces the potential for ocular surface damage resulting from expirations of air reaching the ocular surface during the COVID-19 pandemic.

High performance microscopy for non-invasive conjunctival goblet cell examination examined by study

April 13, 2022

A team of investigators from Pohang University of Science and Technology has found that conjunctival goblet cell examination is important for the precise diagnosis and effective treatment of ocular surface diseases; however, CGC examination has not been possible until now due to lack of non-invasive devices.