Weekly review in ophthalmology: 7 May - 13 May
May 13, 2022
An end-of-week review of what happened in ophthalmology from 7 May to 13 May.
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Retina
Making strides in ophthalmology with modern gene therapy techniques
May 16, 2022
Promising gene therapies in development are pinpointing steps in the pathogenic cascades involved in ocular diseases, such as VEGF for wet AMD and CFI for dry AMD.
Promising early data with intravitreal diabetic macular ischaemia candidate
May 12, 2022
An ischaemia modulator has demonstrated it is safe and well tolerated in a Phase 1/2a trial in diabetic macular ischaemia patients.
2-year YOSEMITE and RHINE results show faricimab reduces treatment burden in patients with DMO
May 05, 2022
Dr Jennifer I. Lim reviews the 2-year results of the YOSEMITE and RHINE trials, outlining the efficacy, durability, and safety of faricimab in diabetic macular oedema.
Testing spectacle lenses for myopia control in relation to changes in axial length
May 04, 2022
Dr Eva Chamorro points out that myopia control spectacle lenses affect the diurnal rhythms in the AL in young adult human and produced a small short-term increase in the AL that varies in intensity and time interval for each of the 3 studied lenses.
Predicting metastasis with novel prognostic liquid biopsy for uveal melanoma
May 04, 2022
Investigators from the Karolinska Institutet and St. Erik Eye Hospital, Stockholm, Sweden, reported that they have developed a prognostic test, referred to as serUM, that they believe is a strong predictor of metastasis of uveal melanoma.
Diabetic rats protected from macular oedema hallmarks with THR-687 treatment
May 03, 2022
THR-687 is currently being evaluated in a phase 2 clinical trial in patients with DME. The first data from the dose-optimization study is expected to be released in the first half of 2022.
Tackling today’s top challenges of clinical research
May 03, 2022
Mike Watson, Vice President of OraNet, unpacks some of the most pressing challenges to clinical research in today’s climate.
Investigators examine long-term effects of anti-VEGF injection on renal function
May 03, 2022
The study found no association between treatment and the risk of chronic kidney disease or end-stage renal disease.
Relationship between dry eye disease and high myopia in teenagers investigated in study
May 03, 2022
In a poster presented at the Association for Research in Vision and Ophthalmology’s 2022 annual meeting, Dr Osama Ibrahim Hirayama and colleagues offered results that demonstrating that anisometropia and astigmatic error were greater among the patients with high myopia compared with the other groups. Compared with the subjects with no myopia, those with high myopia reported significantly more dryness, less photophobia, and less pain.