Retina

The phase 3 LUCERNE and TENAYA trials suggested that faricimab may allow clinicians to extend the interval between injections to up to 16 weeks after an initial loading phase

In an established animal model of age-related macular degeneration, Eleva’s recombinant human CPV-104 improved two hallmarks of the disease

Alcon acquired the historic ophthalmic instrument company in 2000

Bangalore-based Eyestem will share more research findings on Eyecyte-RPE at this year's Association for Research in Vision and Ophthalmology meeting

The company's therapeutic candidates include a bispecific antibody to target vascular retinal diseases

In the European Union and the United Kingdom, aflibercept 8 mg (Eylea HD in the US) is currently approved for neovascular age-related macular degeneration and diabetic macular oedema

Fundus images of diabetic retinopathy were assessed by general ophthalmologists, retina specialists and the Aireen artificial intelligence system

Retina topics serve as the backbone of the scientific programme at this year’s Congress on Controversies in Ophthalmology

Regulatory agencies issued approvals for new treatments and expanded uses of existing therapies in the retina space

Both trials failed to meet their primary endpoints for treatment of age-related macular degeneration

This year, the COPHy meeting moves beyond retina, addressing uveitis, neuro-ophthalmology and glaucoma in Seville, Spain

Researchers assessed the costs to patients and caregivers in Germany, Bulgaria and the US

The approval makes ILM-Blue the first DORC posterior dye product available in China, according to a press release from Zeiss

The authors examined vascular and neural structures in the eye, assessing the foveal avascular zone and choroidal thickness

The synthetic opsin was packaged into an optimised AAV2 gene therapy vector that targets human retinal bipolar cells.

The partnership will use ocular imaging to build an AI foundation model and identify new genetic targets for degenerative diseases

The Combination OPT-302 with Aflibercept Study (COAST) evaluated sozinibercept 2 mg in combination with aflibercept 2 mg for wet age-related macular degeneration

The study demonstrated that the number of injections needed gradually decreased during the follow-up period

Inherited retinal diseases have disease processes distinct from age-related macular degeneration and geographic atrophy, but may present with "phenocopy" clinical signs

Investigators measured the choroidal structures using enhanced depth imaging optical coherence tomography

SpliceBio continues to actively enroll patients in the ASTRA study and accompanying POLARIS trial

A clinician panel illuminates current treatment paradigms and best practices for reducing treatment burden

Additionally, the prognosis of macular oedema may help clinicians evaluate renal function, investigators reported

Clinicians react to the US approval of revakinagene taroretcel-lwey (Encelto; Neurotech Pharmaceuticals) for macular telangiectasia type 2

The event will include presentations on artificial intelligence, ocular imaging and surgical topics

The encapsulated cell therapy from Neurotech Pharmaceuticals is the first FDA-approved treatment for MacTel

The modifier gene therapies from Ocugen target geographic atrophy and Stargardt disease

One in vitro study included in the manuscript was conducted in collaboration with researchers at the University of Southhampton in the United Kingdom

The investigators' findings suggest that CVI is a valuable noninvasive predictive biomarker for monitoring vascular changes in patients who smoke

The researchers reported a “notable” correlation which could serve as a predictive biomarker