Glaucoma

A review of more than 20,000 glaucoma patients in Germany has discovered that 52.6% have a concomitant diagnosis of dry eye with women more likely to have both diseases than men.

Dr Randolph Evans argues that endocyclophotocoagulation (ECP) is a simple, safe and effective procedure for achieving IOP lowering in patients with medically controlled glaucoma who also require cataract surgery

The pathology of glaucoma is likely to be related to the presence and levels of selenium, according to the results of a study published in the August issue of the British Journal of Ophthalmology.

Application of genetic knowledge holds huge potential for the future and some believe that it has potential to become larger than the pharmaceutical market. Here Dr Alward examines what it has offered for the understanding and future treatment of glaucoma. Until recently, breakthroughs in glaucoma genetics emerged from painstaking family research, with the discovery of LOXL1 being the exception.

A question and answer session with a canaloplasty expert.

NicOx S.A. has signed an agreement with Pfizer Inc to reacquire the full development and commercialization rights to PF-03187207, which has completed two phase II studies in patients with primary open angle glaucoma and ocular hypertension. As part of this agreement, Pfizer has granted NicOx the right to access and use certain proprietary Xalatan (latanoprost) data.

OcumatRx, an early stage company that is developing a medical device that represents a new concept for the permanent treatment of patients with glaucoma, has announced the successful completion of clinical trials for their first device with favourable preliminary safety and tolerability.

Alcon Inc. announced it has discontinued development of anecortave acetate for the reduction of IOP associated with glaucoma.

Ronald Pitts Crick, the ophthalmologist who was behind the development of the operating microscope, has died aged 92.

A study by Italian researchers, the results of which have been published online by Eye, has found that both excimer laser trabeculotomy (ELT) and selective laser trabeculoplasty (SLT) are both equally effective treatment options for primary open angle glaucoma.

Ocular Therapeutics has signed non-disclosure agreements with two of the largest pharmaceutical firms in the world. The unnamed companies are interested in a new treatment approach in the largest of the ophthalmic markets.

Alcon has discontinued development of anecortave acetate for the reduction of intraocular pressure (IOP) associated with glaucoma.

A study reported in the July issue of Ophthalmology, the journal of the American Academy of Ophthalmology correlates the incidence of silent cerebral infarcts (SCI) and visual field loss in patients with normal-tension glaucoma.

Long-term SLT experience

Ocular applications of gene therapies are increasing, as is our understanding of the molecular pathogenesis of glaucoma.

The International Glaucoma Association (IGA) is urging people not to cut back on eye tests due to the recession.

Examing endoscopic cyclophotocoagulation as a treatment for ultra-refractory glaucoma patients.

Some of SLT's leading proponents share their short- and long-term findings with us and discuss the future potential of this treatment.

Looking at OCT as a sensitive diagnostic test for glaucomatous progression.

During the recent ARVO congress, Sylentis provided an update on recent advances made by the company in the development a product for ocular pain associated with dry eye syndrome that addresses TRPV1 receptor, a nociceptor able to transmit stimuli.

Kuldev Singh, MD, Professor of ophthalmology, has been appointed chairman of the Glaucoma Research Foundation (GRF).

Results of the evaluation of two-year post-surgical safety and efficacy of canaloplasty to treat open angle glaucoma (OAG) have been published in the Journal of Cataract and Refractive Surgery. Dr Richard A Lewis et al., concluded that the procedure was safe and effective in reducing IOP in adult OAG patients.

Novagali Pharma, the French pharmaceutical ophthalmic company, is to conduct a Phase III clinical trial of Catioprost (Nova21027) its Investigational New Drug Application (IND).

A look at how to introduce canaloplasty into your surgery; experience from two doctors.

New guidelines, designed to improve the management and diagnosis of chronic open angle glaucoma (COAG) and ocular hypertension have received a cautious commendation from the ophthalmic community.

A worldwide licensing agreement for tafluprost, preserved and preservative-free formulations, has been announced between Merck & Co Inc., and Santen Pharmaceutical Co Ltd.

A Swiss startup company, Sensimed, has developed a novel technology for measuring increases in intraocular pressure.

The investigative research group Catalyst for a Cure has made significant discoveries developing a better understanding of the insidious changes caused by glaucoma and is developing strategies to prevent them.

Dr Christoph Kranemann examines the medium-term success and complication rate of mitomycin-assisted bleb needlings.

While researching the long-suspected gene linked to glaucoma, WDR36, Michael Walter, PhD, and team discovered that the gene STL1 is only one of many other genes in which mutations must take place in order for WDR36 to cause glaucoma.