Less lubricants used with BAK-free meds
October 1st 2014Anti-glaucoma preparations that do not contain benzalkonium chloride (BAK) were associated with a change in lubricant use in a study of 240 glaucoma patients, suggesting reduction in some ocular surface disease symptoms, according to research published online.
Ranibizumab long-term observational data presented
September 19th 2014Long-term observational data presented at the 2014 European Society of Retina Specialists (EURETINA) conference support the safety and efficacy profile of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab (Lucentis, Novartis) for the treatment of appropriate patients across its indications
Dexamethasone implant authorized for DME
September 17th 2014The European Commission has extended marketing authorization for an intravitreal implant with 700 mcg of dexamethasone in an applicator (Ozurdex, Allergan) for the treatment of adults with visual impairment caused by diabetic macular oedema (DME) who have pseudophakia or whose condition is considered insufficiently responsive to or unsuitable for non-corticosteroid therapy.
Age-related HS changes have implications for AMD
August 22nd 2014Researchers examining age-related changes in heparan sulphate (HS) quantity and composition in human Bruch's membrane (BrM) have discovered that the quantity greatly decreases with age, resulting in fewer binding sites for complement factor H (CFH) and affecting the ability of the 402H variant of CFH to bind BrM.