Anti-VEGFs clear bloodstream at different rates
July 17th 2014The systemic pharmacokinetics and pharmacodynamics of three anti-vascular endothelial growth factor (VEGF) treatments after they are administered intravitreally differ in ways that "may provide biological plausibility for potential differences in systemic safety risk," according to recently published research.
Macular disease accounts for nearly 10% of world's blindness
July 11th 2014In 2010, 2.1 million people were blind and 6 million people were visually impaired because of macular diseases other than diabetic maculopathy, according to a meta-analysis conducted by members of the Vision Loss Expert Group of the Global Burden of Disease Study Group.
Corneal topography important to monitor after CXL
July 9th 2014When performing corneal collagen crosslinking (CXL), ophthalmologists should monitor the keratoconus index and the index of height asymmetry garnered from the Scheimpflug camera, because changes in values of these indices are independent from initial corneal thickness.
DQS drops relieve persistent dry eye after LASIK
July 2nd 2014The addition of diquafosol tetrasodium (DQS) to a regimen of artificial tears and sodium hyaluronate helped relieve the symptoms of persistent dry eye in patients who had undergone laser in situ keratomileusis (LASIK), according to recent research.
Positive CHMP opinion for glaucoma drops
June 13th 2014The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion for brinzolamide 10 mg/mL and brimonidine tartrate 2 mg/mL eye drops suspension (Simbrinza, Alcon) to decrease elevated intraocular pressure (IOP) in adult patients with open-angle glaucoma or ocular hypertension, for whom monotherapy provides insufficient IOP reduction.
Once daily solution achieves zero-to-trace cell severity
June 11th 2014Bromfenac ophthalmic solution 0.07% (Pro-Lensa, Bausch + Lomb) used once a day results in zero-to-trace (0–5 cells) cell severity in the anterior chamber following cataract surgery with implantation of a posterior chamber IOL, according to newly published research.
Combined treatment for BRVO reduces re-injection need
June 5th 2014Patients who have macular oedema secondary to branch retinal vein occlusion (BRVO) see improved anatomic and functional outcomes with combined intravitreal bevacizumab (IVB) and intravitreal triamcinolone acetate (IVT) therapy when it is delivered early in the disease process, according to the findings of recently published research.
Stents as effective as two medications in OAG
June 4th 2014Implantation of two trabecular micro-bypass devices (iStent inject, Glaukos) reduced intraocular pressure (IOP) at least as effectively as a fixed combination of latanoprost/timolol in patients who had open-angle glaucoma that was not controlled by one medication, according to a recent study.
Refractive outcome shifts toward myopia after combined surgery
May 30th 2014Postoperative refractive outcome shifts toward myopia in patients being treated for rhegmatogenous retinal detachment (RRD) with the combination of phacoemulsification and pars plana vitrectomy, compared with patients who underwent combined surgery for other vitreoretinal pathologies
Dose-ranging study initiated for glaucoma candidate
May 23rd 2014A Phase II dose-ranging study has been initiated for Amakem Therapeutics? glaucoma drug candidate AMA0076, a highly potent, locally acting Rho Kinase (ROCK) inhibitor designed to reduce intraocular pressure (IOP) while minimizing common ROCK inhibitor side effects such as hyperaemia.
Scleral buckling or PPV can treat rhegmatogenous RD in BD
May 22nd 2014Scleral buckling or pars plana vitrectomy (PPV) can be used to treat rhegmatogenous retinal detachment (RD) associated with Beh?et's disease (BD), according to researchers in the Department of Ophthalmology, Zagazig University, Egypt.
Micro-stent is safe and effective after 2-years
May 21st 2014A supracilliary micro-stent, when implanted in conjunction with cataract surgery, substantially reduces intraocular pressure (IOP) with minimal complications in patients with open-angle glaucoma, according to researchers in Germany and the US.
Valve and implant compared for refractory glaucoma
May 16th 2014Patients with refractory glaucoma in whom a proprietary glaucoma implant was placed needed significantly less adjunctive medication to experience success in treatment compared with those who received a proprietary glaucoma valve. However, fewer of those in the latter group had serious postoperative complications, according to recently published 3-year outcomes.