Detecting glaucoma progression a multi-pronged approach
July 1st 2008Ophthalmologists should assess disease progression in patients with established and suspected glaucoma, should confirm with repeat testing any visual function loss that is seen, should remember that structural measurements have variability, and should consider using structural and functional testing together to detect disease progression.
Beyond the anti-VEGF inhibitors
July 1st 2008New investigative drugs for age-related macular degeneration (AMD) may complement the vascular endothelial growth factor (VEGF) agents, improve the visual results, and require fewer injections. Various routes of administration are under investigation and combination treatments are likely to provide more favourable results.
Microneedles: minimal penetration, optimal delivery
July 1st 2008Microneedles offer a better method of ocular drug delivery than traditional methods, according to research presented during the Ophthalmic Drug Delivery symposium, held on June 30 at a meeting of the Royal Pharmaceutical Society of Great Britain.
Nocturnal, sleeping IOP keeps ophthalmologists up at night
July 1st 2008There is much to be learned about nocturnal-and, more importantly, sleeping-IOP if ophthalmologists are going to optimize glaucoma therapies, said Yaniv Barkana, MD, Department of Ophthalmology, Assaf Harofeh Medical Center, Israel.
Do retina transplants represent the future of retinal degeneration treatment?
July 1st 2008Transplants of foetal retinal cells are an effective treatment for retinal degeneration involving the destruction of photoreceptor cells, according to a report published in the August 2008 issue of the American Journal of Ophthalmology.
Substitute for live animal testing approved
July 1st 2008Live animal testing for ocular safety in the US is to be replaced with bovine corneal opacity and permeability (BCOP) and isolated chicken eye (ICE) assays, which do not involve the use of live animals. These alternative tests are scientifically valid and have acceptance as testing methods from regulatory agencies the Food and Drug Administration (FDA) and the Consumer Product Safety Commission (CPSC).