Cornea

Using in vivo microscopy analysis is a safe and effective diagnostic tool in detecting ocular surface squamous neoplasia (OSSN) characteristics

Penetrating keratoplasty (PKP) triple procedures with a 25G system is a safe and effective treatment option.

Benzalkonium chloride-assisted (BAC) transepithelial collagen crosslinking (CXL) with 0.5% proparacaine drops is less effective than standard CXL in patients with progressive keratoconus

Conjunctival ultraviolet autofluorescence (UVAF) photography is valid and reliable for detecting pre-clinical sunlight-induced UV damage

Er:YAG laser therapy could be an alternative to steam cautery

Several algorithms help physicians base appropriate therapy on signs and symptons

Avoiding permanent damage calls for more aggressive treatment, occasional 'scare' tactic

Dermatologic, cosmetic technologies studied for benefits in meibomian gland dysfunction

Understanding the problems of contact lens induced dry eye

Five steps and the criteria for success, as seen through the eyes of patients and their doctors...

British and German scientists Dr Claus Cursiefen and his colleagues have reported that transplanted corneas are more likely to fail or be rejected in patients whose eyes exhibit abnormal vessel growth, called corneal neovascularization, before surgery.

Innovative pharmacological approaches investigated in haze prevention research

Scientists in The Netherlands have received an innovation grant to finalise the specification of a collagen, derived from fishscale, which will act as an alternative material for cornea regeneration.

Dr Joachim Storsberg at the Fraunhofer Institute for Applied Polymer Research in Germany has developed an artificial cornea. The ophthalmological polymer is designed to bond to the eye but remain unclouded by cells in its centre.

In a sample of moderate evaporative-type dry eye disease patients Enriquez-de-Salamanca et al., elevated five inflammatory molecules. Fracktalkine was demonstrated to be present and elevated in tears in human DED.

Non-incisional treatment preserves the biomechanical integrity of the cornea

Data from an interim analysis

The findings of a case report in Cognitive and Behavioral Neurology may support its authors hypothesis that the primary visual cortex, in which retinal spatial geometry is preserved, is not critical for visual imagery.

Devices address both tissue shortage and transplant demand

What should you be concentrating on with severe corneal burns?

Treating corneal neovascularization and the need for new and better treatments.

Northeastern University engineering professor Jeffrey Ruberti and his research colleagues are breaking new ground in the technique known as "hybrid tissue engineering" by attempting to combine cow tissue with human tissue to produce corneas for human transplant.

Researchers are looking into corneal biomechanics as a means to screen patients for keratectasia. The authors review signal interpretation from a non-contact applanation tonometer as it relates to corneal biomechanical indices such as corneal hysteresis.

Ziemer has launched a new corneal surgery model to expand the capabilities of its LDV Femtosecond laser system.

Confocal microscopy as an evaluation tool of wound healing in corneal surgery

Interim results from a Phase II study by Gene Signal suggest that antisense oligonucleotide GS-101 is safe and effective at inhibiting abnormal corneal new blood vessel growth.

A new technique of intraductal meibomian gland probing using disposable cannulas of various lengths appears highly effective in providing quick and lasting relief from inflammatory sysmptoms of obstructive meibomian gland disease.

An oil-in-water and a corticosteroid were both effective in eliminating the signs and symptoms of lid wiper epitheliopathy after a 1-month active treatment phase in a recent study. Improvement was effectively maintained with the emollient eye drops in all patients over a 12-month period.

The use of hydroxypropyl cellulose can significantly improve the symptoms of dry eye, resulting in increased quality of life.

A recent study showed that moderate to sever dry eye disease can be best treated with anti-inflammatory medications such as topical cyclosporine. According to one ophthalmologist, cyclosporine can significantly limit progression of dry eye disease and should be considered a 'go-to' therapy for this patient population.