Cornea

Ocular allergy affects the quality of life of millions of people every year. Understanding the different mechanisms involved will increase their future therapeutic options.

The first human clinical trial to preliminarily evaluate the safety and efficacy of cellular therapy with mesenchymal stem cells for the corneal stroma has shown promise.

It is important with corneal angiography to remember that every patient is different so your technique might very slightly from patient to patient.

The European Commission has granted marketing authorisation for cenegermin eye drops (Oxervate, Dompé) for the treatment of moderate to severe neurotrophic keratitis.

Adding objective point-of-care dry eye diagnostics to your practice has deep, measurable effects, including more accurate and consistent IOL power calculations.

A committee of the European Medicines Agency has recommended approval of cenegermin (Oxervate, Dompé) eye drops for neurotrophic keratitis.

Mooren’s ulcers completely healed in 5 patients treated with rituximab after conventional treatment failed, according to researchers.

Failure to follow-up after ophthalmology appointments can damage patients’ health, a new study suggests. “In our view, national consideration should be given to create targets for reporting how well providers are managing follow-up patients,” reported A Davis and colleagues in the journal Eye.

Preliminary studies suggest disulfiram could aid in the treatment of mucous membrane pemphigoid (MMP). Used topically, the drug may inhibit aldehyde deydrogenase (ALDH), which plays a key role in fibrosis, wrote JK Dart, UCL Institute of Ophthalmology, London.

Chloramphenicol remains effective against Gram-positive bacteria, the most common agent in bacterial conjunctivitis, researchers say.

It’s very hard to tell the difference between Fusarium and Aspergillus species with in vivo confocal microscopy (IVCM) of fungal keratitis, researchers say.

Technique targets the main cause of vision degradation and a large clinical series finds positive results.

Further calibrations for the equivalent keratometry readings (EKR) obtained by the Pentacam High Resolution (HR) (Oculus, Germany) should be conducted before they are used for total corneal power assessment in post-LASIK eyes, researchers said.

A new double-arc intrastromal corneal ring segment may help to improve visual outcomes and rehabilitate the physiologic optical surface by remodelling the cornea

Endothelial keratoplasty has become increasingly common in northwestern Italy, paralleling a rise in the demand for corneal surgery, researchers said.

Topography disparity can even provide a useful parameter for diagnosing the subclinical form of the disease, said David P. Piñero, PhD, and colleagues from the Medimar International Hospital, Alicante, Spain.

Corneal asphericity, OCT angiography, and balance control issues in glaucoma patients are analyzed in this industry update roundup.

In a study in mice, researchers at the University of Pittsburgh demonstrated that stem cells harvested from extracted teeth could potentially be used to restore sight.

More research required to clarify the short- and long-term effects of femtosecond laser-assisted cataract surgery (FLACS) on the corneal endothelium.

A single thermodynamic treatment can serve as an effective treatment of MGD and the beneficial effects of the treatment can last for 6 months or longer.

Researchers at the University of Reading, UK, report that they have discovered a potential way of making eye drops more effective.

Optimal resistance to in vitro keratolysis by collagenase A can be achieved by collagen crosslinking the deepithelialized anterior corneal surface for 30 minutes, according to a recently published study.

Studies with follow-up of 2 to 6 years show that corneal crosslinking for progressive keratectasia is safe and induces long-term structural changes.

Aganirsen eye drops inhibited corneal neovascularization in patients with keratitis and reduced the need for transplantation in patients who have viral keratitis and central neovascularization, according to a Phase III study of 69 patients.

Fasting significantly reduces the amount of tears produced by the eye and increases the osmolarity of the tears, according to new research.

The addition of diquafosol tetrasodium (DQS) to a regimen of artificial tears and sodium hyaluronate helped relieve the symptoms of persistent dry eye in patients who had undergone laser in situ keratomileusis (LASIK), according to recent research.

Currently, there is no treatment to promote the healing of endothelial cells, however, the extent of the corneal oedema can be controlled. In this article, Prof. Feinbaum discusses a new treatment option aimed at alleviating complications of visual loss and pain secondary to corneal oedema.

As the population is living for longer after cataract surgery, Dr Kugelberg and colleagues believed that a longer follow-up period was required to determine PCO rates in three different IOLs. Here, she discusses the highlights of this study.

The arrival of advanced therapeutic modalities for keratoconus has provided ophthalmologists with a growing menu of treatment options. The author discusses the challenge of determining which treatment is the best to use and highlights his experience with a triple procedure and a four-stage approach.

Predicting the position of an iris-fixated pIOL is important to ensure intraocular structure health is maintained. In this article, Dr Soltani Moghadam describes his recent study that found AS-OCT imaging technique to be particularly useful as a preoperative simulation technique.