Link discovered between eye health, diet and lifespanJune 21st 2022
According to investigators, a key reason for the link may lie in circadian “clocks,” the molecular machinery within every cell of every organism, which have evolved to adapt to daily stresses, such as changes in light and temperature caused by the rising and setting of the sun.
Brolucizumab-dbll 6 mg approved by US FDA for treatment of diabetic macular oedemaJune 2nd 2022
According to Novartis, the approval is based on year 1 data from the Phase III KESTREL and KITE clinical trials investigating brolucizumab-dbll 6 mg vs aflibercept 2 mg in diabetic macular oedema patients.
Ill-timed corneal crosslinking led to permanent changes in corneal structure in patients with keratoconusMay 29th 2022
The study evaluates three separate cases, each of which experienced irreversible changes in their corneal structure caused by challenges in getting timely treatment due to various reasons, including insurance, lost to follow up, and the COVID-19 pandemic.
Cost of treatment discourages adherence for patients with dry eye disease associated with Sjögren’s syndromeMay 28th 2022
In a paper, investigators identified strategies used by patients to reduce the cost of therapy and its impact on adherence to treatment. Patients may be reluctant to disclose challenges regarding adherence to dry eye disease therapy, as well as fears of worsening quality of life.
Nanoemulsion formulation enhances IOP reduction, study findsMay 7th 2022
In research sponsored by Skye Bioscience Inc., investigators at the University of Mississippi have demonstrated stronger and longer-lasting reduction of intraocular pressure when a proprietary molecule, SBI-100, is formulated as a nanoemulsion containing the mucoadhesive agent Carbopol 940.
First paediatric patient dosed in BRILLIANCE Phase 1/2 clinical trial for LCA10April 16th 2022
The trial marks the first-ever in vivo delivery of an experimental CRISPR gene editing medicine to a paediatric patient, with the company on track to complete dosing of the paediatric mid-dose cohort in the first half of 2022.
High performance microscopy for non-invasive conjunctival goblet cell examination examined by studyApril 13th 2022
A team of investigators from Pohang University of Science and Technology has found that conjunctival goblet cell examination is important for the precise diagnosis and effective treatment of ocular surface diseases; however, CGC examination has not been possible until now due to lack of non-invasive devices.
Japanese investigators identify gene required for survival of retinal ganglion cellsMarch 27th 2022
A team of investigators at the Okinawa Institute of Science and Technology Graduate University in Japan have identified a gene necessary for the survival of retinal ganglion cells—a class of neurons located in the retina that are critical for vision.
Phase II corneal health clinical program initiated for pharmaceutical platformMarch 16th 2022
Glaukos Corp’s iLink therapy for the treatment of keratoconus consists of novel single-use drug formulations that are bio-activated by proprietary systems through the delivery of ultraviolet light to the cornea to induce corneal cross-linking designed to strengthen, stabilise and reshape the cornea.