ARVO 2024: An adaptable deep learning model for geographic atrophy segmentation

News
Video

Qinqin Zhang, PhD, presented on a deep learning model for GA segmentation at this year's ARVO meeting

The Eye Care Network spoke with Qinqin Zhang, PhD, at this year's ARVO meeting. At the conference in Seattle, Washington, she presented a poster titled "A unified deep learning model for geographic atrophy segmentation: Adaptable to SS-OCT and SD-OCT data with multiple scan patterns." Here, she gives an overview of her presentation and its applications in geographic atrophy (GA).

Editor's note: The below transcript has been lightly edited for clarity.

Qinqin Zhang, PhD: Hi, my name is Qinqin Zhang. I'm a senior application data scientist at Carl Zeiss Meditec. So thank you for giving me this opportunity to present our work. So at ARVO in Seattle, I'm presenting a paper titled, "A unified deep learning model for geographic atrophy segmentation: Adaptable to SS-OCT and SD-OCT data with multiple scan patterns." So, in this paper, we will describe a deep learning model combined with the OCT technique to accomplish automatic and the precise assessment or deletion.

So, the goal was to train a deep learning model that can adjust the micro scan patterns or spectral domain OCT and the swept-source OCT images to automatically and reliably segment GA. To achieve this goal, we extracted 3 features from the oct volume data. So, what is [the] retinal thickness value that can detect the changes from retinal layers and the other is the optical attenuation coefficient values that can detect the abnormality IP layers and the sub IP layers that can capture the hyper transmission defects to detect the other attendees they incur the layers. So by combining these 3 features, a color image was generated and fed into the AI model. So we tune the hyper meter audit model based on the ground truth generated by the clinical expert. So then we can get automatically segmentation on the GA and then mirror size.

The results of this research achieved a high sensitivity of 0.99, and a high specificity of 0.93 on eye level detection or the GA with a high DSC of 0.92 compared to the ground truths. That is indicating a high accuracy in segmenting GA. So this is exciting, because this model the holds promise as a valuable management tool for GA segmentation, monitoring, and also detection. So with adaptability with respect to spectral domain OCT and swept-source, OCT and other scan patterns. So, we are excited to present at ARVO and hopefully that will be beneficial to the attendance here. Thank you.

Newsletter

Join ophthalmologists across Europe—sign up for exclusive updates and innovations in surgical techniques and clinical care.

Recent Videos
Christine Curcio, PhD, of the University of Alabama at Birmingham Heersink School of Medicine, shares histology update and revised nomenclature for OCT with Sheryl Stevenson of the Eye Care Network and Ophthalmology Times
SriniVas R. Sadda, MD, FARVO, shares key points from his retina presentation at the International SPECTRALIS Symposium
Robert Sergott, MD, describes fluorescence lifetime imaging ophthalmoscopy (FLIO) and the International SPECTRALIS Symposium – And Beyond (ISS) in Heidelberg, Germany.
Rayaz Malik, MBChB, PhD, a professor of medicine at Weill Cornell Medicine - Qatar, spoke with Ophthalmology Times Europe about his presentation. It's titled "An eye on neurodegenerative diseases: Challenging the dogma" at the International SPECTRALIS Sympsoium. In conversation with Hattie Hayes, Ophthalmology Times Europe
Anat Loewenstein, MD, describes her presentation on remote imaging for age-related macular degeneration and geographic atrophy at the International SPECTRALIS Symposium, in conversation with Hattie Hayes of Ophthalmology Times Europe
Tyson Brunstetter, OD, PhD, a US Navy Aerospace Optometrist at the NASA Johnson Space Center in Houston, Texas, shares key takeaways from his keynote at the International SPECTRALIS Symposium (ISS)
Rayaz Malik, MBChB, PhD, shares his presentation, titled An eye on neurodegenerative diseases: Challenging the dogma, at this year's International SPECTRALIS Symposium
At the Retina World Congress, Siegfried Priglinger, MD, speaks about ensuring the best outcomes for preschool-aged patients
At the 2025 ASCRS meeting, Robert Ang, MD said small aperture IOLs can benefit all patients, especially those with complex corneas or who have undergone previous corneal refractive surgery
Viha Vig, MBChB graduate student at the University of Auckland, New Zealand, discusses her poster presentation on the relationship between mitochondiral disease, Alzheimer disease, and other types of dementia.
Related Content
© 2025 MJH Life Sciences

All rights reserved.