Articles

Three separate studies on eye health examine the role of antioxidant supplements, the relationship of visual acuity and mortality, and the causes of glaucoma in the May 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.

A five-minute test in which a patient is tilted produces peak IOP detection levels comparable to standard water drinking tests, according to a poster presented at this year's meeting of the Association for Research in Vision and Ophthalmology.

Gene therapy has been used successfully to improve visual function in a patient with a genetic disorder of the retina, Leber's congenital amaurosis (LCA), as reported in a study published online ahead of print by the New England Journal of Medicine.

VEGF Trap (Regeneron) maintains a significant improvement in the visual acuity of neovascular age-related macular degeneration (wet AMD) patients up to 32 weeks, according to a study presented at this year's Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO).

Xibrom (bromfenac 0.09 mg ophthalmic solution; ISTA Pharmaceuticals) significantly improves visual acuity outcomes and lowers retreatment rates when administered as an adjuvant to Lucentis (ranibizumab; Novartis) therapy in neovascular age-related macular degeneration (AMD) patients, when compared with Lucentis monotherapy, according to a poster presented at this year's Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO).

On April 28, a meeting of the FDA Ophthalmic Devices Panel confirmed that a study investigating patient satisfaction and quality of life post-LASIK is to be conducted in the US by a Joint LASIK Study Task Force.

Gebauer has launched an extension to its single-use SL Keratome, enabling surgeons to perform corneal transplantation surgery with its new, combined single-use DSAEK/ALK set and reusable artificial anterior chamber.

Cataractogenesis may be the result of the interaction of crystallin-derived peptides with intact crystallins in the lens, according to a study published in the March 2008 issue of the Journal of Biological Chemistry.

The Collaborative Initial Glaucoma Treatment Study (CIGTS) showed that substantially lowering IOP, whether through medication or surgery, can prevent vision loss. One of the major trials of recent years, CIGTS also showed that surgery was an effective first-line treatment and had important findings on quality of life.

The iCare tonometer (Tiolat) has been approved for use in China by the country's State Food and Drug Administration (SFDA); the tonometer is now approved in every major global market.

The presence of benzalkonium chloride (BAK) has no impact on the safety or efficacy of travoprost in lowering intraocular pressure (IOP), according to a study published in the April/May 2008 issue of the Journal of Glaucoma.

Paediatric cataract surgery, particularly when performed in patients under the age of nine months, entails a substantial risk of post-surgical glaucoma, according to a study published in the January 2008 issue of Investigative Ophthalmology and Visual Science.

Young male glaucoma sufferers are most likely to discontinue their treatment at a glaucoma clinic during the first year of follow-up, according to a study published in the April/May 2008 issue of the Journal of Glaucoma.

The American Society of Cataract and Refractive Surgery (ASCRS) survey results for 2008 pointed out some changing trends in infectious keratitis after LASIK and PRK compared with previous surveys conducted in 2002 and 2005, said Terry Kim, MD.

Outcomes in a cohort including more than 5000 eyes support the conclusion that an implantable collamer lens (Visian ICL; STAAR Surgical) is a safe, predictable, and very effective method for correcting high-to-moderate myopia, said John R. Moran, MD, PhD.

Hypoesthesia is not the origin of post-LASIK punctuate epithelial keratopathy or the so-called dry eye syndrome. Rather, these sequelae may represent a phototoxic effect of treatment with the ultraviolet excimer laser, said Carmen Barraquer-Coll, MD.

Highlights from the ASCRS meeting, held 4–8 April 2008, Chicago, US.

Early experience from a pilot study shows that spherocylindrical error after cataract surgery can be corrected with a proprietary light-adjustable lens (LAL; Calhoun Vision) to improve uncorrected visual acuity (UCVA), said Arturo S. Chayet, MD.

Lucentis (ranibizumab; Novartis) is to be made available to patients of the National Health Service (NHS) in England and Wales. The final appraisal document (FAD) has been published ahead of a final decision, expected in June 2008.

Orbis International, an international nonprofit humanitarian organization which operates the world"s only Flying Eye Hospital, is to upgrade from a DC-10-10 to a DC-10 Series 30 freighter airline, giving the project an extra 20 years of flying time.

Sometimes I sit back and think about how this magazine has evolved over the years and, on a more regular basis, I think about where we can go from here.

Refractive surgeons should be aware of the possibility that a surgical marker pen (Codman; Johnson & Johnson) could be a cause of diffuse lamellar keratitis (DLK) after LASIK, said Wei-Han Chua, MD.

Canaloplasty with tensioning suture placement is growing in popularity owing to a combination of factors, including a successful training programme, an improved reimbursement picture, and favourable long-term data, said Richard A. Lewis, MD.

An aspheric IOL may be considered the implant design of choice for most patients with glaucoma who require cataract surgery, said Richard L. Lindstrom, MD.

The injection of DNA into the optic nerve resulted in light perception vision in patients with no light perception and very low vision, according to Sunita Agarwal, MD.

Nutritional supplements seem to make sense as a treatment of tear dysfunction, according to Marian Macsai, MD. Dr Macsai tempered her assertion with the observation that no objective trials have been performed to support the use of nutritional supplements in patients with tear deficiency.

Second Sight's "bionic eye" implant, the Argus II Retinal Prosthesis System, has been implanted into two blind patients at London's Moorfields Eye Hospital by Dr Lyndon da Cruz and team.

Spectral domain, three-dimensional (3-D), high-resolution optical coherence tomography (OCT) represents a step forward in OCT technology, with precise registration, complete data set acquisition, and improved coverage of the retina being the major advantages.

VEGFb, a novel form of vascular endothelial growth factor (VEGF), an anti-angiogenic which is cytoprotective for retinal cells, can inhibit choroidal neovascularization significantly, according to preclinical results presented at this year's BIO National Venture Conference, held April 22?23 in Cambridge, US.

Cortiject, Novagali Pharma's investigational treatment for Diabetic Macular Oedema (DME), has successfully been injected into the first patient in its Phase I clinical trial.