Positive family history increases likelihood of visual field loss at presentation
May 16th 2008Patients with a positive family history of glaucoma are 10 times as likely to have visual field (VF) defects at the time of their diagnosis, according to a study published in the April issue of Clinical & Experimental Ophthalmology, the official Journal of the Royal Australian and New Zealand College of Ophthalmologists.
First preservative-free prostaglandin treatment approved
May 16th 2008Taflotan (tafluprost; Santen Oy), a benzalkonium chloride (BAK)-free prostaglandin analogue for the treatment of glaucoma, has received marketing authorization in Denmark and Germany, making it the first preservative-free prostaglandin eye drop to be approved.
VEGF Trap vs. Lucentis: the test begins
May 14th 2008VIEW 2, a Phase III trial evaluating the efficacy and safety of VEGF Trap (afilbercept; Regeneron) versus Lucentis (ranibizumab; Novartis) administered by intravitreal injection for the treatment of neovascular age-related macular degeneration (wet AMD), has dosed its first patient.
Post-LASIK contact lens launched
May 12th 2008A hybrid contact lens designed for eyes that have suffered corneal trauma or undergone either refractive surgery or penetrating keratoplasty has been launched by SynergEyes Inc, US. The SynergEyes PS lens can also be used in eyes with degenerative corneal conditions.
Anterior juxtascleral depot of anecortave acetate reduces IOP significantly
May 9th 2008IOP can be reduced significantly by an anterior juxtascleral depot of anecortave acetate, according to study results presented on a poster at this year's meeting of the Association for Research in Vision and Ophthalmology.
Experimental nitric oxide-donating glaucoma treatment "effective", but Pfizer drops it
May 9th 2008PF-03187207, an experimental glaucoma treatment that was being developed by NicOx and Pfizer, has been shown in Phase II testing to be more effective in lowering IOP under certain circumstances than Pfizer's Xalatan (latanoprost) 0.005%, but it will not be advanced into Phase III testing, Pfizer has announced.
Eye health issues examined in Ophthalmology
May 9th 2008Three separate studies on eye health examine the role of antioxidant supplements, the relationship of visual acuity and mortality, and the causes of glaucoma in the May 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.
Peak IOP can be measured just as well with tilting as with water drinking
May 9th 2008A five-minute test in which a patient is tilted produces peak IOP detection levels comparable to standard water drinking tests, according to a poster presented at this year's meeting of the Association for Research in Vision and Ophthalmology.
Proof that gene therapy can treat genetic disorder of the retina
May 7th 2008Gene therapy has been used successfully to improve visual function in a patient with a genetic disorder of the retina, Leber's congenital amaurosis (LCA), as reported in a study published online ahead of print by the New England Journal of Medicine.
VEGF Trap continues to impress
May 7th 2008VEGF Trap (Regeneron) maintains a significant improvement in the visual acuity of neovascular age-related macular degeneration (wet AMD) patients up to 32 weeks, according to a study presented at this year's Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO).
Xibrom useful adjuvant to Lucentis in treatment of AMD
May 7th 2008Xibrom (bromfenac 0.09 mg ophthalmic solution; ISTA Pharmaceuticals) significantly improves visual acuity outcomes and lowers retreatment rates when administered as an adjuvant to Lucentis (ranibizumab; Novartis) therapy in neovascular age-related macular degeneration (AMD) patients, when compared with Lucentis monotherapy, according to a poster presented at this year's Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO).
Gebauer launches DSAEK/ALK single use set with reusable artificial anterior chamber
May 6th 2008Gebauer has launched an extension to its single-use SL Keratome, enabling surgeons to perform corneal transplantation surgery with its new, combined single-use DSAEK/ALK set and reusable artificial anterior chamber.
CIGTS data: Large IOP reductions, initial trabeculectomy values validated
May 2nd 2008The Collaborative Initial Glaucoma Treatment Study (CIGTS) showed that substantially lowering IOP, whether through medication or surgery, can prevent vision loss. One of the major trials of recent years, CIGTS also showed that surgery was an effective first-line treatment and had important findings on quality of life.
Surgery for paediatric cataract entails increased glaucoma risk
May 2nd 2008Paediatric cataract surgery, particularly when performed in patients under the age of nine months, entails a substantial risk of post-surgical glaucoma, according to a study published in the January 2008 issue of Investigative Ophthalmology and Visual Science.
Infection incidence increasing despite improving diagnoses
May 1st 2008The American Society of Cataract and Refractive Surgery (ASCRS) survey results for 2008 pointed out some changing trends in infectious keratitis after LASIK and PRK compared with previous surveys conducted in 2002 and 2005, said Terry Kim, MD.
Visian ICL "impressive" for myopic correction
May 1st 2008Outcomes in a cohort including more than 5000 eyes support the conclusion that an implantable collamer lens (Visian ICL; STAAR Surgical) is a safe, predictable, and very effective method for correcting high-to-moderate myopia, said John R. Moran, MD, PhD.
UV toxicity culprit in post-LASIK dry eye
May 1st 2008Hypoesthesia is not the origin of post-LASIK punctuate epithelial keratopathy or the so-called dry eye syndrome. Rather, these sequelae may represent a phototoxic effect of treatment with the ultraviolet excimer laser, said Carmen Barraquer-Coll, MD.