Wet AMD sufferers unaware of pre-existing AMD
July 14th 2008Current screening of patients with age-related macular degeneration (AMD) does not sufficiently identify those patients most at risk of wet AMD and hence is unable to prevent its development, according to a report published in the June 2008 issue of Eye.
Low dose Medidur FA safe and effective in DME
July 8th 2008Low doses of Alimera Sciences' Medidur FA provide visual acuity improvements and reduce the risk of ocular side effects commonly associated with corticosteroids, when administered to diabetic macular oedema (DME) patients, according to the three-month interim results of the first human pharmacokinetic (PK) study.
Enzyme therapy could replace surgical vitrectomy
July 8th 2008ThromboGenics' experimental enzyme therapy, microplasmin, has been shown to induce a posterior vitreous detachment (PVD) in over 30% of patients in the high dose group, without the need for surgical intervention, according to the results of the Phase IIb MIVI III (Microplasmin for Vitreous Injection) trial.
Detecting glaucoma progression a multi-pronged approach
July 1st 2008Ophthalmologists should assess disease progression in patients with established and suspected glaucoma, should confirm with repeat testing any visual function loss that is seen, should remember that structural measurements have variability, and should consider using structural and functional testing together to detect disease progression.
Beyond the anti-VEGF inhibitors
July 1st 2008New investigative drugs for age-related macular degeneration (AMD) may complement the vascular endothelial growth factor (VEGF) agents, improve the visual results, and require fewer injections. Various routes of administration are under investigation and combination treatments are likely to provide more favourable results.
Microneedles: minimal penetration, optimal delivery
July 1st 2008Microneedles offer a better method of ocular drug delivery than traditional methods, according to research presented during the Ophthalmic Drug Delivery symposium, held on June 30 at a meeting of the Royal Pharmaceutical Society of Great Britain.
Do retina transplants represent the future of retinal degeneration treatment?
July 1st 2008Transplants of foetal retinal cells are an effective treatment for retinal degeneration involving the destruction of photoreceptor cells, according to a report published in the August 2008 issue of the American Journal of Ophthalmology.
Substitute for live animal testing approved
July 1st 2008Live animal testing for ocular safety in the US is to be replaced with bovine corneal opacity and permeability (BCOP) and isolated chicken eye (ICE) assays, which do not involve the use of live animals. These alternative tests are scientifically valid and have acceptance as testing methods from regulatory agencies the Food and Drug Administration (FDA) and the Consumer Product Safety Commission (CPSC).