Partial pressure of oxygen is significantly higher in African American patients

Article

Ocular oxygen levels are higher in African American patients than in Caucasians.

Ocular oxygen levels are higher in African American patients than in Caucasians, according to a study in the Archives of Ophthalmology.

Dr Carla J. Siegfried et al., Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, USA, used an optical oxygen sensor inserted into the anterior chamber through a peripheral corneal paracentesis to measure partial pressure of oxygen before intraocular cataract/glaucoma surgery.

The flexible fiberoptic probe was used to measure the oxygen pressure in the central corneal endothelium, the mid-anterior chamber and the anterior chamber angle in both glaucoma and cataract patients. Oxygen pressure was measured at the anterior lens and in the posterior chamber situated behind the iris in the cataract patients.

The findings suggest there may be differences in systemic physiologic function. The partial pressure of oxygen was higher in all ocular locations in African American patients compared with Caucasians.

The results indicate an integral difference in oxidative metabolism in the lens and cornea. Oxidative stress, cell damage, intraocular pressure and glaucoma risk may be increased by oxygen or oxygen metabolites.

Recent Videos
Dr Rick Lewis discusses the FLigHT procedure and ViaLase laser at the 2024 European Society of Cataract and Refractive Surgeons (ESCRS) meeting
Christiana Dinah speaks about her ASRS presentation, Real-World Treatment Outcomes With Anti-VEGF Therapy in Patients With Retinal Vein Occlusion in the UK
Chase Ludwig, MD, shared an overview of his presentation, which covered real-impact of vitrectomy surgery on the progression of AMD at the annual ASRS meeting in Stockholm, Sweden
Patrick C. Staropoli, MD, discusses clinical characterisation of Hexokinase 1 (HK1) mutations causing autosomal dominant pericentral retinitis pigmentosa
Richard B. Rosen, MD, discusses his ASRS presentation on illuminating subclinical sickle cell activities using dynamic OCT angiography
ASRS 2024: Socioeconomic barriers and visual outcomes in patients with rhegmatogenous retinal detachments, from Sally S. Ong, MD
Ashkan Abbey, MD, speaks about his presentation on the the CALM registry study, the 36-month outcomes of real world patients receiving fluocinolone acetonide 0.18 mg at the annual ASRS meeting in Stockholm, Sweden.
Nikoloz Labauri, MD, FVRS, speaks at the 2024 ASRS meeting about suspensory macular buckling as a novel technique for addressing myopic traction maculopathy
Jordana Fein, MD, MS, speaks with Modern Retina about the IOP outcomes with aflibercept 8 mg and 2 mg in patients with DME through week 48 of the phase 2/3 PHOTON trial at the annual ASRS meeting in Stockholm, Sweden.
© 2024 MJH Life Sciences

All rights reserved.