Implants lower IOP, reduce medication
December 1st 2010Implanatation of multiple trabecular micro-bypass implants (iStent, Glaukos) in Schlemm's canal following phamoemulsification successfully and significantly reduced IOP for 12 months after implantation, as well as the number of medications required to maintain target IOP
Rates of change may signal POAG
December 1st 2010Analyses of data from the Confocal Scanning Laser Ophthalmoscopy Ancilliary Study to the Ocular Hypertension Treatment study found rim area parameters changed significantly in the eyes that had progression to a primary open-angle glaucoma endpoint compared with eyes that did not.
Gene transfer agent in development
December 1st 2010Results from preclinical testing including a formal Good Laboratory Practice toxicity study, support the safety of a gene transfer agent, AAV2-sFLT01, when administered intravitreally. A phase I safety and tolerability study of this agent is currently underway.