News

The combination of sutureless coaxial microincision cataract surgery and 23-gauge vitrectomy confers many advantages, including less wound leakage, good anterior chamber stability, safety, decreased inflammation and faster rehabilitation after surgery, according to the authors of a study published recently in Retina: The Journal of Retinal and Vitreous Diseases.

Patients who develop advanced age-related macular degeneration (AMD) undergo a precipitous loss of vision, concluded the researchers of this study recently published in the Journal of the American Medical Association Ophthalmology.

Patients with optic disc swelling caused by nonarteritic anterior ischaemic optic neuropathy (NAION) have less light retardance compared with patients with optic disc swelling caused by papilloedema or optic neuritis.

Collagen crosslinking (CXL) in patients with progressive keratoconus was found to be effective after 2 years in improving uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), topographic metrics, and most corneal higher-order aberrations, according to a study published in Cornea: The Journal of Cornea and External Disease. Researchers noted that there was a significant reduction in apical keratometry, which directly correlated with improvements in visual acuity

Autologous serum (AS) eye drops on the ocular surface of patients with bilateral severe dry eye improved not only ocular surface dryness, but decreased damage of the epithelium as well, as measured by clinical, laboratory, and subjective criteria, according to results from a study recently published in Current Eye Research

Steroid-induced central serous chorioretinopathy (CSC) may only occur in select patients who are vulnerable, rather than having a dose-dependent effect, according to a recent study published in Investigative Ophthalmology & Visual Science

Patients with pseudophakic eye who have undergone cataract will have greater access to fluocinolone acetonide (Iluvien, Alimera Sciences) for the treatment of chronic diabetic macular oedema (DME) that is considered refractive to available therapies. The National Institute for Health and Care Excellence (NICE) has published a final guidance recommending fluocinolone acetonide, making it available for patients through the National Health Service (NHS).

All anti-vascular endothelial growth factor (VEGF) agents improve visual acuity compared with laser photocoagulation, but there is insufficient evidence to distinguish the performance of any single anti-VEGF agent over another, according to results from a recently-conducted meta-analysis from researchers at the Institute for Clinical and Economic Review. The safety of bevacizumab also remains uncertain.

Despite treatment, chloroquine retinopathy may continue to progress long after drug cessation, according to a study published on-line by the British Journal of Ophthalmology. Further, disease progression may be accompanied by cystoid macular oedema, epiretinal membrane formation and peripheral involvement.

Small incision lenticule extraction (SMILE) caused less keratocyte apoptosis, proliferation and inflammation compared with femtosecond laser LASIK, according to data from a recent animal model study.

The Home Monitoring of the Eye (HOME) study, conducted in AREDS2 clinical centres, has demonstrated that patients at high-risk of developing choroidal neovascularization (CNV) - the neovascular or wet phase of AMD - benefit from using the ForeseeHome monitoring device (Notal Vision).

According to recently published data, anti-VEGF therapy is superior to laser photocoagulation for the treatment of moderate-to-severe visual impairment caused by diabetic macular oedema (DME).

Roche has announced additional encouraging results of a phase II study with lampalizumab to treat patients with geographic atrophy (GA). The MAHALO study data was presented during the Retina subspeciality day at AAO 2013 in New Orleans, Louisiana, USA.

2013 has been an important year in retina therapy, with increased information released on nutritional supplements for AMD patients, widened indications for anti-VEGFs and the approval of treatment for symptomatic vitreomacular adhesion.

Replacing monovision

The availability of newer presbyopia solutions such as corneal inlays has changed the landscape of presbyopia treatment and is now allowing us to offer our patients a better quality of vision.

In this article, the authors review the various corticosteroid options and attempt to determine their place in the therapeutic regimen.

Meeting Review

Ophthalmologists from 76 countries discussed the latest findings in diagnostics and therapy, and also issues of promoting the next generation of young ophthalmologists.

Advancements in cataract surgery have always been surrounded by passionate debate with arguments for and against new technologies and techniques. In this article, the authors discuss their recent study in which they examined the evolution of cataract surgery and controversy surrounding it.

Major geographical differences exist worldwide in cases of cataracts and macular degeneration, according to the largest-ever analysis of worldwide vision impairment and blindness, which was recently published in The Lancet Global Health journal.

Progranulin, a protein found in fat-derived stem cells, may reverse and perhaps prevent age-related, light-induced retinal damage, according to results from a study done in a mouse model by researchers from Gifu Pharmaceutical University and Gifu University, Japan.