European Commission expands upadacitinib (Rinvoq) indication to include giant cell arteritis
Patients with GCA, an autoimmune disease, are at risk for sudden vision loss which can be permanent
Tenpoint Therapeutics submits US FDA New Drug Application for presbyopia treatment BRIMOCHOL PF
Following Phase 3 pivotal trial BRIO-II, Tenpoint Therapeutics said they hope to launch BRIMOCHOL PF in 2026
Paediatric patients with early-onset atopic dermatitis show higher uveitis risk
The study findings support the need to consider ophthalmologic monitoring in children with early-onset atopic dermatitis
Canalicular gel Lacrifill (Nordic Pharma) receives CE Mark
Nordic Pharma plans to announce commercialisation details in the near future for the dry eye disease treatment
A real-world study of an AI system for enhanced detection of diabetic retinopathy
Fundus images of diabetic retinopathy were assessed by general ophthalmologists, retina specialists and the Aireen artificial intelligence system
A panel discussion on extended treatment intervals in retinal therapy breaks the mold at COPHy 2025
Treatment regimens with long-duration therapies continue to be a conversation starter among retina specialists
How embracing opposition sends clinicians home from COPHy with more useful takeaways
The Congress on Controversies in Ophthalmology highlights debates, but also discussions
Surgical, medical and next-generation retina topics at COPHy
Retina topics serve as the backbone of the scientific programme at this year’s Congress on Controversies in Ophthalmology
Retina recap: EMA and US FDA approvals, March 2025
Regulatory agencies issued approvals for new treatments and expanded uses of existing therapies in the retina space
US FDA issues second Complete Response Letter for dry eye drug reproxalap (Aldeyra Therapeutics)
Aldeyra previously received a CRL for its initial New Drug Application for reproxalap in November 2023
Opthea discontinues COAST and ShORe sozinibercept combination therapy trials
Both trials failed to meet their primary endpoints for treatment of age-related macular degeneration
French OPHTAMYOP study reveals trends in myopia control
How studies into myopia management can increase access to vision care
EMA grants positive CHMP opinion for low-dose atropine SYD-101 (Ryjunea, Sydnexis)
A pivotal phase 3 clinical trial found that SYD-101 met its 3-year primary endpoint for slowing paediatric myopia progression
New study investigates ocular involvement in multiple myeloma
Hematologists and ophthalmologists could work together for earlier diagnoses, research findings indicate
Up for debate: Clinicians take on hot topics at the Congress on Controversies in Ophthalmology
This year, the COPHy meeting moves beyond retina, addressing uveitis, neuro-ophthalmology and glaucoma in Seville, Spain
International study illuminates economic burden of late-stage age-related macular degeneration
Researchers assessed the costs to patients and caregivers in Germany, Bulgaria and the US
Accommodative intraocular lenses: Are they coming back?
A resurgence in this IOL technology could create new possibilities in refractive correction
Paediatric myopia study indicates lens thickness and power changes closely associated with age
The study assessed a large paediatric cohort for changes in spherical equivalent refraction, axial length, lens power and lens thickness
Alcon acquires majority interest in cell therapy company Aurion Biotech, provides operational updates
AURN001 is Aurion Biotech's clinical-stage allogeneic cell therapy asset for corneal oedema secondary to corneal endothelial disease
Internal limiting membrane staining dye ILM-Blue from DORC (Zeiss) receives NMPA approval in China
The approval makes ILM-Blue the first DORC posterior dye product available in China, according to a press release from Zeiss
Association between dry eye, ophthalmic structures and fibromyalgia syndrome
The authors examined vascular and neural structures in the eye, assessing the foveal avascular zone and choroidal thickness
Nanoscope Therapeutics publishes clinical results of MCO-010 findings for patients with retinitis pigmentosa
The synthetic opsin was packaged into an optimised AAV2 gene therapy vector that targets human retinal bipolar cells.
Alcon Clareon Vivity IOL receives CE mark, European commercialisation announced
The lens will be available with the Monarch IV manual delivery system in Q2 and the AutonoMe Automated Pre-Loaded Delivery System in Q3
Moorfields Eye Hospital INSIGHT research hub will collaborate with artificial intelligence development company Insitro
The partnership will use ocular imaging to build an AI foundation model and identify new genetic targets for degenerative diseases
Phase 3 COAST trial fails to meet primary endpoints for wet AMD, Opthea reports
The Combination OPT-302 with Aflibercept Study (COAST) evaluated sozinibercept 2 mg in combination with aflibercept 2 mg for wet age-related macular degeneration
Study examines real-world treat-and-extend outcomes and background factors of macular atrophy
The study demonstrated that the number of injections needed gradually decreased during the follow-up period
Increased paediatric astigmatism prevalence and severity after COVID-19
The study findings indicated that lifestyle changes associated with the COVID-19 pandemic were connected to an increase in childhood astigmatisms
Researchers raise awareness of macular pathologies which mimic AMD and GA
Inherited retinal diseases have disease processes distinct from age-related macular degeneration and geographic atrophy, but may present with "phenocopy" clinical signs
Three researchers receive 2025 ARVO Foundation Early Career Clinician-Scientist Awards
The award recipients are leading research projects in India, Italy and Mexico
Bausch + Lomb launches Arise orthokeratology lens fitting system in Europe, UK and US
The Arise system utilises advanced algorithms to interpret corneal topography images, recommending lenses without requiring a fitting set
