Articles

The size and binding characteristics of proteins are likely to influence their ability to penetrate the eye from the periocular space, but in general, proteins as large as 50-75 kDa penetrate well into the choroid but not into the retina.

Reichert has received 510k clearance from the FDA to market the Reichert-Optopol Spectral Optical Coherence Tomographer (SOCT) in the US.

Sirion Therapeutics has entered into an exclusive agreement with Bridge Pharma for the worldwide rights to develop and market topical ophthalmic formulations containing Bridge's proprietary anti-inflammatory agent norketotifen.

Preoperative tear volume may affect recovery of the ocular surface after LASIK and could increase the risk for chronic dry eye.

Topical levofloxacin penetrates better than ofloxcin or ciprofloxacin into the aqueous of eyes with functioning filtering blebs.

Six-month data for myopia treatments with the SCHWIND AMARIS laser show that it is effective and patient friendly.

Clinicians have an array of techniques and devices available to them for assessing progression of glaucoma, and more are under development. Such tools rely on either subjective or objective measurements, with the latter generally providing more reliable results. Frequent, long-term follow-up with one or more of those approaches will increase the likelihood of detecting progression early.

Alcon has announced positive efficacy and safety results from its second controlled proof of concept clinical study of anecortave acetate administered as an anterior juxtascleral depot in the sub-Tenon's space to reduce intraocular pressure (IOP) in patients with open-angle glaucoma.

Patients with established glaucoma have only slightly greater knowledge of their condition than patients who are newly diagnosed.

Ocular motility abnormalities and strabismus are common in children after aqueous drainage device surgery and these problems should be taken into account before proceeding with surgery.

It is recommended that all babies with retinopathy of prematurity (ROP) be screened at 12 months to identify amblyogenic factors such as squint and refractive error.

Age, independent of the duration of uveitis, is a major risk factor for the presence of cystoid macular oedema (CME) in uveitis.

Preliminary results of a study using the NSAID Xibrom (bromfenac ophthalmic solution 0.09%; ISTA Pharmaceuticals) therapy in combination with Lucentis (ranibizumab; Novartis) in patients with wet age-related macular degeneration (AMD), suggests that it may result in fewer injections being required.

Bausch & Lomb has acquired eyeonics, the maker of the crystalens accommodating IOL.

Diffuse lamellar keratitis (DLK) occurs more frequently after LASIK performed with the IntraLase 15 kHz femtosecond laser than after LASIK performed with the Moria M2 microkeratome.

Female cataract surgery patients are more likely to assess their postoperative visual function as worse than male patients.

March's research news

The M2 microkeratome (Moria), the Carriazo-Pendular microkeratome (Schwind) and the IntraLase femtosecond laser all create flaps of predictable thickness.

Incision sizes needed to remove cataracts have been significantly reduced by new technology, such as the vision enhancement system (Stellaris; Bausch & Lomb) which allows surgeons to make two 1.8 mm cuts on either side of the eye.

According to an article in UK newspaper The Sunday Times, blind children in the UK are being taught to "see" by using the same method used by bats, dolphins, and whales: clicking their tongues.

Oxidative stress is an early event in hydrostatic pressure/intraocular pressure-induced (IOP) neuronal damage.

April Editorial List

When the amount of optic nerve damage is taken into account, there is little difference in the optic disc topography of patients with primary open-angle glaucoma (POAG) and those with primary angle-closure glaucoma.

Optic disc pit prevalence increases with age and is strongly associated with high-pressure open-angle glaucoma.

Twenty-three gauge transconjunctival sutureless vitrectomy is an effective surgical technique for the management of vitreoretinal diseases.

A blind person's sight has been restored by surgeons at the University Hospitals of Geneva (HUG) for the first time in Europe using American technology.

MacuSight has announced positive preliminary data from the Phase I study of its lead product candidate for wet age-related macular degeneration (AMD), sirolimus.

A study published in the January issue of Antimicrobial Agents & Chemotherapy, has found that the high proportion of corneal infections linked to contact lens solutions are fuelled and made resistant to treatment by the formation of a highly resistant structure of microbial cells held together with a glue-like matrix material, called biofilms.

The use of glaucoma drainage surgery is decreasing in Britain, which may be explained by an increase in cataract extraction, according to a report published in the January issue of Eye.

Using a telemedicine system to assist ophthalmologists in developing countries with the diagnosis and management of various ophthalmic conditions can be successful.