Prostaglandin analogue use has grown at the expense of beta-blockers and trabeculectomy in Scotland

Article

The increasing use of prostaglandin analogues in Scotland has led to an increase in prescribing rates and a rapid increase in cost, whilst prescribing of beta-blockers has declined and trabeculectomy rates have fallen, according to a study published in the February 2008 issue of Eye.

The increasing use of prostaglandin analogues in Scotland has led to an increase in prescribing rates and a rapid increase in cost, whilst prescribing of beta-blockers has declined and trabeculectomy rates have fallen, according to a study published in the February 2008 issue of Eye.

Dr Shona Macleod of Aberdeen Royal Infirmary and University of Aberdeen, Scotland and team evaluated the changing trends in glaucoma management in Scotland between 1994 and 2004 by conducting a retrospective analysis of national health statistics. The outcome measures were trabeculectomy rates, corrected for population likely to be at risk of glaucoma (PLG), prescribing volume and cost for glaucoma medications.

Between 1994 and 2004, PLG (calculated from estimates of prevalence in individuals aged 40 years and older, based on published epidemiological studies) increased by 16.6%. During the same time period, trabeculectomy rates fell from 46 per 1000 PLG in 1994 to 15.4 per 1000 PLG in 2004, a decrease of 67%. The cost of prescribing increased by 122% compared with an increase in number of items per 1000 PLG by 27.5%.

In 1994, beta-blockers accounted for 65.2% of prescribed drugs; by 2004, this had dropped to 33%. Since their introduction, the prescribing of prostaglandin analogues has increased rapidly and in 2004, they accounted for 39.4% of prescribed drugs.

Thus the rapidly rising cost of prostaglandin analogues has not impacted negatively on their use, which had in fact, by 2004 in Scotland, overtaken the prescribing of the more traditional beta-blockers and trabeculectomies.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Jeremiah Tao, MD, FACS, discusses his Egyptian Ophthalmological Society keynote, which focused on risk management and avoiding surgical complications in oculofacial surgery
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
João Pedro Marques, MD, MSc, PhD discusses a retrospective study of 800 patients with inherited retinal diseases during the American Society of Retina Specialists (ASRS) annual meeting
© 2025 MJH Life Sciences

All rights reserved.