News

iCo-007, the experimental intravitreal injection for the treatment of diabetic macular oedema (DME), has produced pleasing interim trial results and been approved to progress to the third stage of the Phase I study, according to a statement released by the drug's licence holder, iCo Therapeutics Inc.

Body mass influences IOP

The body mass index (BMI) of a patient may affect the results of a water-drinking test (WDT), according to study results published in October issue of the Journal of Ocular Pharmacology and Therapeutics.

The two Phase III trials of Iluvien (fluocinolone acetonide; Alimera Sciences Inc) in diabetic macular oedema (DME) have been assessed for safety and efficacy by an independent Data Safety Monitoring Board and are to progress without change.

Comparing GAT with DCT

Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) do not produce identical results when measuring intraocular pressure (IOP), according to study results published in the September 2008 issue of the Journal of Glaucoma.

Intraocular lenses (IOLs) soaked in antibiotics have antimicrobial properties, according to results published in the October issue of the Journal of Ocular Pharmacology and Therapeutics.

Postoperative visual acuity (VA) is the factor with the most significant impact on stereopsis in paediatric unilateral pseudophakic subjects, according to study results published online ahead of print by the British Journal of Ophthalmology.

Amaris is the first refractive laser in the world to offer two separate energy levels for optimal corneal smoothing, according to an announcement from Schwind, the laser's manufacturer.

An Indian doctor is planning to perform 200 cataract extractions free of cost within 15 hours in November in order to secure a place in the Guinness Book of World Records.

Figure 2

Ablation simulation

New beta-blocker trialled

Othera Pharmaceuticals' topical beta blocker, OT-730, indicated for the reduction of intraocular pressure (IOP) in subjects with ocular hypertension and open-angle glaucoma, has begun a Phase I/II clinical trial for safety and efficacy.

Visual loss in subjects with diabetic retinopathy (DR) is caused by factors other than the disease, according to study results published in the September issue of Investigative Ophthalmology & Visual Science.

SOLX 790, a glaucoma laser, has received 510(k) clearance from the FDA and can now be used for Titanium:Sapphire laser trabeculoplasty (TLT) in the United States, the laser's manufacturer, SOLX, has announced.

NT-501, a Ciliary Neurotrophic Factor (CNTF)-releasing polymer indicated for the treatment of visual loss in retinitis pigmentosa (RP) and dry age-related macular degeneration (AMD), has been granted a Fast Track designation by the FDA, Neurotech Pharmaceuticals Inc, the compound's manufacturer, has announced.

Figure 1

Height and fit data

Markus Schill, PhD and Clemens Wagner, PhD of VRMagic GmbH have received the European VitreoRetinal Society's annual Relja Zivojnovic Award for outstanding contributions to the field of vitreoretinal surgery.

ESCRS 2008

Highlights from the 2008 congress of the European Society of Cataract and Refractive Surgery

It's all changing at Zeiss

Recent acquisitions, division restructuring, and management changes prove that Carl Zeiss Meditec is very much committed to change. Ophthalmology Times Europe spoke with CEO, Dr Michael Kaschke about the challenges that he faces in an ever evolving market.

Dr Rudi Nujits, presented new research on femtosecond laser assisted Descemet Stripping Endothelial Keratoplasty (FS-DSEK) at a session on the femtosecond laser and therapeutic corneal surgery.

Oertli proudly showcased their new product that enables coaxial microincision cataract surgery through 1.6 mm: the CO-MICS 2 tip is fully compatible with the firm's existing OS3, SwissTech and CataRhex platforms.

OcuSense, makers of the innovative TearLab Osmolarity System for the diagnosis of dry eye, announced the signing of multi-year agreements with four distributors in five EU countries, for the exclusive distribution of the TearLab system.

The "One" range of single-use ophthalmic instruments has been introduced by Moria. The range comprises instruments commonly used during cataract surgery; instruments are available individually, or as part of a custom pack.

The search for a presbyopic treatment that is universally effective and universally applicable is viewed in the industry and the profession as the holy grail because of the number of people in the presbyopic age group today.

The age of microkeratomes is coming to an end as femtosecond lasers come of age. That's the chief conclusion drawn by Dr Gunther Grabner, professor of ophthalmology at the Paracelsus University of Salzburg, in a survey on the advantages and limitations of femtosecond lasers.

Refractive outcomes for Femtosecond Lenticule Extraction (FLEx) are getting close to those of eximer-based Femto-LASIK, and patients are expressing high degrees of satisfaction with both techniques, Dr Walter Sekundo told delegates at a session on current trends in laser refractive surgery.

Bimanual microincision cataract surgery (MICS) and microaxial phacolemulsification provide optically better incisions but bimanual MICS respects more corneal prolateness than microaxial phaco, Mr Jorge Alio, told delegates. "MICS is associated with less corneal oedema in the short term and less inducation of corneal aberrations in the long term," he said.

In a worldwide first, Dr Luis Ruiz presented the preliminary clinical results of an ongoing pilot study concentrating on the non-invasive intrastromal correction of presbyopia.

Ophthalmology is perhaps two steps closer to a possible clinical application of lens refilling with silicon gel for restoring ocular accommodation thanks to a refined procedure developed by Dr Okihiro Nishi, MD of the Nishi Eye Hospital, Japan.