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ZEISS Clinical Cases|

Heidelberg Engineering: Enhancing the Patient Journey

Opinion|Videos|February 7, 2025

Outcomes with Raricimab and Choosing Between the New Therapies

Author(s)John Kitchens, MD, Richard Gale, PhD, MEd, BSc, MBChB, FRCP, FRCOphth, Michael W. Stewart, MD

Panelists discuss how faricimab’s dual inhibition of Ang-2 provides additional benefits in vascular stability and inflammation reduction beyond VEGF-A suppression alone, potentially leading to improved durability and treatment outcomes in selected patients.

Episodes in this series

3 experts are featured in this series.

EP. 1 Evolution of Anti-VEGF Agents and Unmet Needs in Retinal Diseases

3 experts are featured in this series.

EP. 2 Advantages of the Molecular Structure of Aflibercept

3 experts are featured in this series.

EP. 3 Treat-and-Extend Strategy With Aflibercept

3 experts are featured in this series.

EP. 4 Assessing New Therapies for Retinal Diseases

3 experts are featured in this series.

EP. 5 Significance of the Higher Molar Dose of Aflibercept 8 mg

3 experts are featured in this series.

EP. 6 Study Design for PULSAR and PHOTON Trials for Aflibercept 8 mg

3 experts are featured in this series.

EP. 7 Patient Selection for Aflibercept 8 mg

3 experts are featured in this series.

EP. 8 Faricimab Molecular Design and Role of Ang-2

3 experts are featured in this series.

EP. 9 Outcomes with Raricimab and Choosing Between the New Therapies

3 experts are featured in this series.

EP. 10 Safety Profile of New Therapies

3 experts are featured in this series.

EP. 11 Perspectives on the Usefulness of Real-world Data

3 experts are featured in this series.

EP. 12 Strategies for Loading Dose Sse for Treatment-Naive and Switch Patients

3 experts are featured in this series.

EP. 13 Impact of Durable Therapies on Patients and Clinics and Monitoring Strategies

Video content above is prompted by the following:

In clinical trials, faricimab showed noninferior vision outcomes compared to aflibercept 2 mg. What added benefit do you see by targeting Ang-2?

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