News

Bottles of infected eye drops are more likely to be contaminated with bacteria at the bottle tip and not within the solution, according to a study presented at this year's American Society of Cataract and Refractive Surgery (ASCRS) meeting.

The Tube versus Trabeculectomy (TVT) Study found that nonvalved tube shunt surgery was more likely to maintain IOP control and avoid persistent hypotony and reoperation for glaucoma than trabeculectomy with mitomycin C (MMC) during the first year of follow-up.

Hi-Tech Pharmacal Co., Inc. has announced that the FDA has granted tentative approval to the company's Abbreviated New Drug Application (ANDA) for dorzolamide hydrochloride with timolol maleate ophthalmic solution, the generic equivalent of Merck's Cosopt.

Regeneration of damaged retinal cells with the aid of stem cells may offer hope for the treatment of retinal degeneration conditions, such as age-related macular degeneration (AMD) and diabetic retinopathy (DR), according to a report published by the National Academy of Sciences (Volume 103).

Intravitreal medical therapy for age-related macular degeneration (AMD) is dominated by the two anti-vascular endothelial growth factor (VEGF) drugs, ranibizumab and bevacizumab (Lucentis and Avastin, respectively, Genentech).

Novartis is to purchase 25% of Alcon from majority stakeholder Nestlé, with an option to purchase Nestlé's remaining shares, which currently amount to approximately 52% of Alcon.

A new study assessing the quality of life after LASIK is to be conducted by the American Society of Cataract and Refractive Surgery (ASCRS), the American Academy of Ophthalmology, the FDA and the National Eye Institute, it was announced at this year's ASCRS meeting in Chicago, US.

A clinical trial of Xibrom (bromfenac sodium ophthalmic solution; ISTA Pharmaceuticals) has demonstrated equivalence of end-point achievement between the 0.18% and the 0.09% formulations, according to topline results published by ISTA Pharmaceuticals.

Intraocular pressure (IOP) lowering drugs are more effective in eyes with low central corneal thickness (CCT) than those with high CCT, according to a study published in the March issue of Journal of Glaucoma.

NeoVista Inc?s epiretinal brachytherapy for wet AMD in combination with Avastin (bevacizumab) has been shown to improve mean visual acuity (VA) in patients, with adverse events restricted to vitrectomy-related problems and not to radiation toxicity, according to results of a Phase II trial presented at the 31st Annual Macula Society Meeting in Palm Beach, Florida, US.

Lucentis (ranibizumab; Novartis) is to be made available to all patients of the National Health Service (NHS) in England and Wales, according to a report from the BBC. The final appraisal document (FAD) has been published ahead of final guidance, expected in June 2008.

Following designation of New Technology Intraocular Lens (NTIOL) status by the Centers for Medicare and Medicaid Services (CMS), AMO has introduced the Tecnis 1-Piece IOL to the US market.

Swiss researchers have identified the defect in the coding region of the gene responsible for childhood cataract by assessing family members who suffered from autosomal dominant juvenile cataract, according to a study published in the March 2008 issue of the American Journal of Human Genetics.

PresbyLASIK or multifocal IOL implantation yield superior visual outcomes in patients with presbyopia, improving both near and distance vision, as opposed to accommodative IOL implantation, which improves distance vision only, according to a study published in the March 2008 issue of the Journal of Refractive Surgery.

Injection-related complications such as infectious endophthalmitis, retinal detachment, and traumatic cataract may occur with a frequency of about 0.15% after intravitreal injections of bevacizumab or triamcinolone, independently of the drug injected, according to a study published in the February issue of Eye.