Two-quadrant anaesthesia technique reduces pain during vitrectomy

Article

Using two-quadrant sub-Tenon's anaesthesia is more effective at reducing intraoperative and postoperative pain than a single-quadrant technique.

Using two-quadrant sub-Tenon's anaesthesia is more effective at reducing intraoperative and postoperative pain than a single-quadrant technique, states a study in the British Journal of Ophthalmology.

Dr Vip S. Gill et al., Department of Anaesthesia, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK, studied 54 patients undergoing vitrectomy. All patients were equally randomized into two groups.

Group A, the control, were administered a standard 5 ml single inferonasal sub-Tenon injection of 2% lidocaine and 0.5% bupivacaine in a 50:50 mixture. Group B, the study group, received a 5 ml inferonasal and 5 ml superotemporal injection.

Primary outcome measures included amount of intraoperative top-ups needed and the secondary outcome measures included intraoperative and postoperative pain scores, IOP, block onset time, ocular akinesia, eyelid akinesia and chemosis.

In the group V there were no patients requiring an anaesthetic top-up, but in the control group a top-up was needed in 24 patients. In group B block onset was shorter, eyelid akinesia was improved and pain scores were reduced intraoperatively and 0–2 hours (h), 4–6 h, 10–14 h and 20–24 h postoperatively.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
EURETINA 2025: Boris Stanzel, MD, methotrexate is rocking the European retina landscape
Jeremiah Tao, MD, FACS, discusses his Egyptian Ophthalmological Society keynote, which focused on risk management and avoiding surgical complications in oculofacial surgery
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
© 2025 MJH Life Sciences

All rights reserved.