Triamcinolone associated with few side effects

Intravitreal triamcinolone acetonide (IVTA) for the treatment of steroid-responsive disorders of the posterior segment is associated with a low incidence of serious vision-threatening adverse events.

Intravitreal triamcinolone acetonide (IVTA) for the treatment of steroid-responsive disorders of the posterior segment is associated with a low incidence of serious vision-threatening adverse events, according to a report published in the January issue of Retina.

Daniel Roth of the Robert Wood Johnson Medical School, New Jersey, USA and colleagues retrospectively reviewed the medical records of 784 patients (929 consecutive eyes) who had received one or more IVTA injections for a steroid-responsive posterior segment disorder.

The most common adverse event occurring within three months of the initial injection was steroid-related ocular hypertension, with intraocular pressure spikes of >21 mmHg in 21% of eyes and >25 mmHg in 11% of eyes. Ocular inflammation was observed in six eyes (0.6%) and three eyes (0.3%) had corneal epithelial defects thought to be related to pretreatment with povidone-iodine solution. No eyes had culture-positive infectious endophthalmitis.

When administered under sterile conditions, concluded the authors, IVTA is associated with a low incidence of serious adverse events.

Related Videos
Fluid dynamics in wet macular degeneration: How fluid type affects visual acuity
EURETINA leadership discusses what to expect at the 2022 Congress, outlines Women in Retina programme
Paediatric eyes repair better with scleral buckling, adults need vitrectomy only for giant retinal tear-related detachments
Clinical trials in wet AMD: Impact of central subfield thickness, volatility on visual acuity
Post hoc analysis of Copernicus, Galileo trials find time since diagnosis affects BCVA outcomes in CRVO
Related Content
© 2023 MJH Life Sciences

All rights reserved.