Aberration-correcting IOLs are more sensitive to decentration and tilt, according to a paper in the 

Journal of Cataract and Refractive Surgery

Dr David Madrid-Costa and his team, Optics Department, University of Valencia, Valencia, Spain, completed a cohort study on 10 eyes of 10 patients. Two aspheric aberration-correcting IOLs and two spherical IOLs were tested on all patients. The outcome measures included monocular distance visual acuity at 100%, 50% and 10% and depth of focus.

After centration of the IOLs there were no differences in visual acuity between all four IOLs. However, both aberration-correcting were found to be more sensitive to tilt and decentration than the spherical IOLs.

The results demonstrated that higher residual spherical aberration slightly improved depth of focus and defocus tolerance. Visual quality in the eyes with aspheric aberration-correcting IOLs presented with corneal higher-order aberrations in those who have an average human cornea.

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Cataract & Refractive

Aberration-correcting IOLs are more sensitive to decentration and tilt