Rigid gas permeable lens highly influences the interpretation of CXL results

Article

Wearing a rigid gas permeable lens can lead to improved topographic parameters and can significantly alter a number of study parameters.

Wearing a rigid gas permeable lens can lead to improved topographic parameters and can significantly alter a number of study parameters, claims a paper published in the British Journal of Ophthalmology.

A prospective, non-comparative study led by Dr Koppen Carina, Department of Ophthalmology, Antwerp University Hospital, Belgium, comprised of 15 eyes without rigid gas permeable contact lens (CL) and 12 eyes fitted with a CL from 1 to 10 weeks after ultraviolet A/riboflavin cross-linking (CXL) for the stabilisation of progressive keratoconus.

Refractive sphere and cylinder, maximal keratometry value (K max), simulated keratometry steep, flat, astigmatism, refractive power (RP) steep, flat and astigmatism, I-S value on EyeSys, K max on Pentacam and change from baseline of best spectacle-corrected visual acuity (BSCVA) were all used to measure the effect of CXL treatment on patients. The results of the study were recorded pre-CXL and in 6 month intervals for 18 months post-CXL.

There were no study parameters that demonstrated a significant change from baseline results in eyes without CL.

However, in eyes fitted with CL post-CXL I-S value and K max on EyeSys at all time intervals, RP steep and simulated astigmatism at 6 and 12 months and RP flat at 12 months all showed significant improvement.

CL can greatly influence the interpretation of CXL results, with lens wear improving topographic parameters.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Christine Curcio, PhD, of the University of Alabama at Birmingham Heersink School of Medicine, shares histology update and revised nomenclature for OCT with Sheryl Stevenson of the Eye Care Network and Ophthalmology Times
SriniVas R. Sadda, MD, FARVO, shares key points from his retina presentation at the International SPECTRALIS Symposium
Robert Sergott, MD, describes fluorescence lifetime imaging ophthalmoscopy (FLIO) and the International SPECTRALIS Symposium – And Beyond (ISS) in Heidelberg, Germany.
Rayaz Malik, MBChB, PhD, a professor of medicine at Weill Cornell Medicine - Qatar, spoke with Ophthalmology Times Europe about his presentation. It's titled "An eye on neurodegenerative diseases: Challenging the dogma" at the International SPECTRALIS Sympsoium. In conversation with Hattie Hayes, Ophthalmology Times Europe
Anat Loewenstein, MD, describes her presentation on remote imaging for age-related macular degeneration and geographic atrophy at the International SPECTRALIS Symposium, in conversation with Hattie Hayes of Ophthalmology Times Europe
Tyson Brunstetter, OD, PhD, a US Navy Aerospace Optometrist at the NASA Johnson Space Center in Houston, Texas, shares key takeaways from his keynote at the International SPECTRALIS Symposium (ISS)
Rayaz Malik, MBChB, PhD, shares his presentation, titled An eye on neurodegenerative diseases: Challenging the dogma, at this year's International SPECTRALIS Symposium
At the Retina World Congress, Siegfried Priglinger, MD, speaks about ensuring the best outcomes for preschool-aged patients
At the 2025 ASCRS meeting, Robert Ang, MD said small aperture IOLs can benefit all patients, especially those with complex corneas or who have undergone previous corneal refractive surgery
Viha Vig, MBChB graduate student at the University of Auckland, New Zealand, discusses her poster presentation on the relationship between mitochondiral disease, Alzheimer disease, and other types of dementia.
© 2025 MJH Life Sciences

All rights reserved.