Pupil size affects coma value in certain eyes

Article

When compared with eyes of normal axial length, high-myopic pseudophakic eyes with posterior staphyloma had significantly less internal coma and less coma variations during mydriasis, according to recently published research.

When compared with eyes of normal axial length, high-myopic pseudophakic eyes with posterior staphyloma had significantly less internal coma and less coma variations during mydriasis, according to research published in Eye.

The researchers studied 60 eyes: 40 in highly myopic cataract patients with posterior staphyloma and 20 in cataract patients with normal axial length.

They found that the high-myopic pseudophakic eyes with posterior staphyloma had significantly lower values of internal coma - both under 4 mm and 6 mm pupil sizes - at 1 month after phacoemulsification and IOL implantation compared to eyes with normal axial length.

The high-myopic pseudophakic eyes with posterior staphyloma also had significantly lower internal total higher-order aberrations and third-order aberrations at 6-mm pupil size.

In addition, the researchers found statistically significant differences between the two groups in the variation from 4- to 6-mm pupil sizes for:

  • internal coma
  • internal third-order aberrations

  • internal total higher-order aberrations
  • ocular coma aberrations.

Strehl ratio increased significantly in high-myopic eyes and decreased slightly in normal axial length eyes after mydriasis, and modular transfer functions were found to vary in a statistically significant manner between the two groups at frequencies of 15, 30, 45 and 60 cycles/degree.

To read an abstract of the study, click here.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Andreas Pollreisz, MD, discusses widefield OCT-A and fluorescence angiography at the 2025 European Society of Retina Specialists EURETINA meeting
Harvey Uy, MD, DPBO, FVRSP, speaks about artificial intelligence (AI) and optical coherence tomography (OCT) at the 2025 European Society of Retina Specialists (EURETINA) Congress.
EURETINA 2025: Boris Stanzel, MD, methotrexate is rocking the European retina landscape
© 2025 MJH Life Sciences

All rights reserved.