PED volume and area changes could indicate retreatment

Volume and area changes in retinal pigment epithelial detachments (PEDs) could indicate the need for retreatment in eyes undergoing SD-OCT guided anti-VEGF therapy, according to a paper in Retina.

Dr Fernando Penha et al., Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA, conducted a retrospective study on fourteen eyes with PEDs undergoing SD-OCT with anti-VEGF treatment.

Decision to retreat the eyes was determined by qualitative assessments of fluid in the macula. The team retrospectively analysed SD-OCT images from the 57 visits where treatment was withheld. A novel algorithm was used to measure the area and volume of the PEDs.

The PED volume increased at the eighth visit when the SD-OCT algorithm evaluated the scans and treatment was required at the next follow-up visit. For the remaining 49 visits, where treatment was withheld, PED volume did not increase and no additional treatment was required.

To read the abstract please click here.