PED volume and area changes could indicate retreatment

Mar 05, 2013

Volume and area changes in retinal pigment epithelial detachments (PEDs) could indicate the need for retreatment in eyes undergoing SD-OCT guided anti-VEGF therapy.

Volume and area changes in retinal pigment epithelial detachments (PEDs) could indicate the need for retreatment in eyes undergoing SD-OCT guided anti-VEGF therapy, according to a paper in Retina.

Dr Fernando Penha et al., Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA, conducted a retrospective study on fourteen eyes with PEDs undergoing SD-OCT with anti-VEGF treatment.

Decision to retreat the eyes was determined by qualitative assessments of fluid in the macula. The team retrospectively analysed SD-OCT images from the 57 visits where treatment was withheld. A novel algorithm was used to measure the area and volume of the PEDs.

The PED volume increased at the eighth visit when the SD-OCT algorithm evaluated the scans and treatment was required at the next follow-up visit. For the remaining 49 visits, where treatment was withheld, PED volume did not increase and no additional treatment was required.

To read the abstract please click here.

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