OCLR and Scheimpflug-Placido topographer effective for corneal measurements

Article

Using an optical low-coherence reflectometry (OLCR) biometer and Scheimpflug-Placido topographer are both as effective for measuring corneal parameters

Using an optical low-coherence reflectometry (OLCR) biometer and Scheimpflug-Placido topographer are both as effective for measuring corneal parameters, claims a study in the Journal of Cataract and Refractive Surgery.

Dr Wuhe Chen et al., Eye Hospital of Wenzhou Medical College, Wenzhou, China, evaluated 40 subjects. One randomly healthy eye of each participant was measured three times with both devices.

The parameters measured included central corneal thickness (CCT), anterior chamber depth (ACD) from the corneal epithelium and from the endothelium, mean keratometry (K) and white-to-white (WTW) corneal diameter.

Within-subject standard deviation was used to calculate the repeatability of the scans. Agreement between the two devices was evaluated using the Bland-Altman limits of agreement (LoA) method. A mean of three scans were performed in order to assess LoA.

Repeatability of the Scheimpflug-Placido topographer and OLCR biometer was 3.10 μm and 3.32 μm for CCT. For WTW corneal diameter was 0.04 mm and 0.05 mm and for mean K it was 0.17 D and 0.10 D for mean K for the the Scheimpflug-Placido topographer and OLCR biometer, respectively.

According to the Bland-Altman LoA analysis, all parameters were within clinically sufficient limits. Both devices presented good repeatability for all parameters and can be used interchangeably between parameters.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Jeremiah Tao, MD, FACS, discusses his Egyptian Ophthalmological Society keynote, which focused on risk management and avoiding surgical complications in oculofacial surgery
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
João Pedro Marques, MD, MSc, PhD discusses a retrospective study of 800 patients with inherited retinal diseases during the American Society of Retina Specialists (ASRS) annual meeting
© 2025 MJH Life Sciences

All rights reserved.