Non-surgical periocular nodular-BCC treatments are successful

Article

Imiquimod (IMQ) 5% cream and radiotherapy (RT) are both effective for treating periocular nodular-based cell carcinoma (BCC)

Imiquimod (IMQ) 5% cream and radiotherapy (RT) are both effective for treating periocular nodular-based cell carcinoma (BCC), according to a study published in the British Journal of Ophthalmology.

Dr Elena Garcia-Martin et al., Hospital Universitario Miguel Servet, Zaragoza, Spain, examined 27 patients with clinical and histopathological diagnosis of nodular BCC on the eyelid. IMQ 5% cream was administered in 15 patients once daily 5 days a week for 6 weeks. RT was performed in 12 patients.

Within 3 months of treatment all patients demonstrated histopathological remission. Sustained clinical remission was recorded in every patient after 24 months follow-up. Toleration of treatment for IMQ and RT was recorded as moderate and good, respectively.

The investigation concluded that the non-surgical methods of using IMQ and RT were successful in treating eyelid nodular BCCs. IMQ demonstrated better cosmesis and functional results, whereas RT demonstrated a better tolerability.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
EURETINA 2025: Boris Stanzel, MD, methotrexate is rocking the European retina landscape
Jeremiah Tao, MD, FACS, discusses his Egyptian Ophthalmological Society keynote, which focused on risk management and avoiding surgical complications in oculofacial surgery
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
© 2025 MJH Life Sciences

All rights reserved.