Laser-assisted capsulotomy results better than CCC

Article

Femtosecond laser-assisted capsulotomy resulted in better circularity and more predictable size compared with standard manual continuous curvilinear capsulorhexis (CCC) in a prospective, randomized clinical study by researchers in Italy.

Femtosecond laser-assisted capsulotomy resulted in better circularity and more predictable size compared with standard manual continuous curvilinear capsulorhexis (CCC) in a prospective, randomized clinical study by researchers in Italy. They also found that IOL centration was better immediately following surgery and over time for patients who underwent femtosecond laser-assisted capsulotomy. The results are published in the Journal of Cataract & Refractive Surgery.

Candidates for cataract extraction were randomly assigned into 1 of 3 groups, each with 30 eyes of 30 patients:

  • Laser group 1 underwent femtosecond laser–assisted cataract surgery capsulotomy performed with a proprietary laser (LenSx, Alcon),

  • Laser group 2 had femtosecond laser–assisted cataract surgery capsulotomy performed with a proprietary laser (Lensar Laser System, Lensar Inc.), and

  • The manual group underwent manual CCC.

After 7 days, the capsulotomies in both laser groups showed significantly better circularity than did those the CCCs of the manual group. The two laser groups also showed a significant correlation between the intended versus achieved capsulotomy size as well as better IOL centration than the manual group at all timepoints.

Distance visual acuity, both corrected and uncorrected, was not different in a statistically significant way between groups. Residual spherical equivalent and mean absolute error, however, were statistically significantly smaller in the laser groups than in the manual group, and they increased significantly over time in all the groups.

Newsletter

Join ophthalmologists across Europe—sign up for exclusive updates and innovations in surgical techniques and clinical care.

Recent Videos
Christine Curcio, PhD, of the University of Alabama at Birmingham Heersink School of Medicine, shares histology update and revised nomenclature for OCT with Sheryl Stevenson of the Eye Care Network and Ophthalmology Times
SriniVas R. Sadda, MD, FARVO, shares key points from his retina presentation at the International SPECTRALIS Symposium
Robert Sergott, MD, describes fluorescence lifetime imaging ophthalmoscopy (FLIO) and the International SPECTRALIS Symposium – And Beyond (ISS) in Heidelberg, Germany.
Rayaz Malik, MBChB, PhD, a professor of medicine at Weill Cornell Medicine - Qatar, spoke with Ophthalmology Times Europe about his presentation. It's titled "An eye on neurodegenerative diseases: Challenging the dogma" at the International SPECTRALIS Sympsoium. In conversation with Hattie Hayes, Ophthalmology Times Europe
Anat Loewenstein, MD, describes her presentation on remote imaging for age-related macular degeneration and geographic atrophy at the International SPECTRALIS Symposium, in conversation with Hattie Hayes of Ophthalmology Times Europe
Tyson Brunstetter, OD, PhD, a US Navy Aerospace Optometrist at the NASA Johnson Space Center in Houston, Texas, shares key takeaways from his keynote at the International SPECTRALIS Symposium (ISS)
Rayaz Malik, MBChB, PhD, shares his presentation, titled An eye on neurodegenerative diseases: Challenging the dogma, at this year's International SPECTRALIS Symposium
At the Retina World Congress, Siegfried Priglinger, MD, speaks about ensuring the best outcomes for preschool-aged patients
At the 2025 ASCRS meeting, Robert Ang, MD said small aperture IOLs can benefit all patients, especially those with complex corneas or who have undergone previous corneal refractive surgery
Viha Vig, MBChB graduate student at the University of Auckland, New Zealand, discusses her poster presentation on the relationship between mitochondiral disease, Alzheimer disease, and other types of dementia.
© 2025 MJH Life Sciences

All rights reserved.