GMS+ implantation not effective for IOP control

Article

Gold Micro Shunt Plus (GMS+) implantation is not an effective method for controlling IOP in glaucoma patients, according to a recent study in the journal BMC Ophthalmology.

Gold Micro Shunt Plus (GMS+) implantation is not an effective method for controlling IOP in glaucoma patients, according to a recent study in the journal BMC Ophthalmology.

Dr Arno Hueber et al., Department of Ophthalmology, University of Cologne, Germany, conducted a retrospective study on 31 eyes of 31 patients with severe glaucoma and uncontrolled IOP. Each patient underwent GMS+ implantation by means of a full-thickness scleral flap. The main outcome measures were surgical failure or success, determined by intraocular pressure and adverse effects.

Of the eyes included in the study, 30 met one of the failure criteria. Additional surgery was performed due to elevated IOP in 24 eyes and adverse effects in 2 eyes.

The remaining four eyes presented with an IOP reduction of less than 20% with comparable medication. The team explanted six GMS+’s because of IOP elevation in 2 eyes, rubeosis in 2 eyes and low-grade inflammation in 2 eyes.

GMS+ implantation is not effective for the control of IOP in glaucoma patients and the reason for the appearance of low grade inflammation and rubeosis iridis in 4 eyes remains unknown.

To read the abstract please click here.

Recent Videos
(Image credit: Ophthalmology Times Europe) AGS 2025: Clemens Strohmaier, PhD, on improving aqueous humour outflow following excimer laser trabeculostomy
Anat Loewenstein, MD, speaks about the 22nd Annual Angiogenesis, Exudation, and Degeneration Meeting in February 2025 and shares her global forecast for AI-driven home OCT
Sarah M. Thomasy, DVM, PhD, DACVO, a veterinary ophthalmologist at UC Davis, talks about how her research at the Glaucoma 360 symposium
I. Paul Singh, MD, an anterior segment and glaucoma specialist, discusses the Glaucoma 360 conference, where he participated in a panel discussion on the use of artificial intelligence (AI) in glaucoma care.
Charles Wykoff, MD, PhD, discusses his Floretina ICOOR presentation topic, retinal non-perfusion in diabetic retinopathy, with David Hutton, editor of Ophthalmology Times
Elizabeth Cohen, MD, discusses the Zoster Eye Disease study at the 2024 AAO meeting
Vikas Chopra at AAO 2024: Advancements in MIGS are transforming patient care
Victoria L Tseng, MD, PhD, professor of ophthalmology and glaucoma specialist, UCLA
© 2025 MJH Life Sciences

All rights reserved.