Focal loss of laminar beams could cause lamina cribosa deformation


Lamina cribosa (LC) deformation in glaucoma can be caused by focal loss of laminar beams

Lamina cribosa (LC) deformation in glaucoma can be caused by focal loss of laminar beams, claims a study in the Archives of Ophthalmology.

Dr Saman Kiumehr et al., Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, USA, included 92 eyes of 31 patients. Of the patients studied, 46 were healthy control subjects and 45 were glaucomatous.

Optical coherence tomography images of the optic nerve head were obtained from both groups of patients. Focal LC defects were defined as anterior laminar surface irregularities, sptial consistency, neuroretinal rim thinning/notching and visual field defects.

There were 98 focal LC defects found in 34 glaucomatous eyes and seven of the 11 glaucomatous eyes had a deeply excavated optic disc. Focal LC defects mostly occurred in the inferior or inferotemporal far periphery of the LC.

It was found that focal LC defects limited to the inferior half of the optic disc typically have greater sensitivity loss in the superior visual hemfield. Focal LC defects tend to occur in correlation with neuroretinal rim and visual field loss.

Related Videos
ARVO 2024: Andrew D. Pucker, OD, PhD on measuring meibomian gland morphology with increased accuracy
 Allen Ho, MD, presented a paper on the 12 month results of a mutation agnostic optogenetic programme for patients with severe vision loss from retinitis pigmentosa
Noel Brennan, MScOptom, PhD, a clinical research fellow at Johnson and Johnson
ARVO 2024: President-elect SriniVas Sadda, MD, speaks with David Hutton of Ophthalmology Times
Elias Kahan, MD, a clinical research fellow and incoming PGY1 resident at NYU
Neda Gioia, OD, sat down to discuss a poster from this year's ARVO meeting held in Seattle, Washington
Eric Donnenfeld, MD, a corneal, cataract and refractive surgeon at Ophthalmic Consultants of Connecticut, discusses his ARVO presentation with Ophthalmology Times
John D Sheppard, MD, MSc, FACs, speaks with David Hutton of Ophthalmology Times
Paul Kayne, PhD, on assessing melanocortin receptors in the ocular space
Osamah Saeedi, MD, MS, at ARVO 2024
© 2024 MJH Life Sciences

All rights reserved.