'Experienced' patients still have difficulty administering glaucoma drops

Article

Even patients experienced with instilling topical glaucoma medications continue to have difficulties with eye drop administration, even those who do not self-report such difficulties, according to a recent study. Further, the risk of having difficulties with eye drop instillation is increased in patients who self-report difficulty and in those who have been previously observed to have difficulties.

Even patients experienced with instilling topical glaucoma medications continue to have difficulties with eye drop administration, even those who do not self-report such difficulties, according to a recent study published in Current Medical Research and Opinion. Further, the risk of having difficulties with eye drop instillation is increased in patients who self-report difficulty and in those who have been previously observed to have difficulties.

For this multicenter, investigator-masked, randomized, controlled trial, 164 patients with glaucoma or ocular hypertension were included. Patients were randomized to 12 weeks of treatment with topical ocular hypotensive medication.

At baseline, patients were given a self-assessment questionnaire designed to determine their difficulty with drop administration. At baseline and at 12 weeks, patients demonstrated their drop instillation efficacy using a bottle of artificial tears.

A full 50% of patients had already undergone treatment with an ocular hypotensive medication for ≥ 3 years. At study entry, only 11.4% reported having difficulties with eye drop administration. At baseline, 18.2% touched their eye/adnexa with the bottle and 10.3% missed the eye. At 12 weeks, 18.5% and 8.6% of patients had these problems, respectively.

Overall, difficulty with drop instillation was seen in 42.1% of patients. Difficulty at both visits was seen in 35.3% of patients who reported difficulties at study entry, and in 17.2% of patients who reported no difficulties. Relative risk of demonstrating difficulty at either visits was 2.0 times greater for patients with self-reported difficulties at study entry (P = 0.004). Relative risk of demonstrating difficulty at week 12 was 3.8 times greater for patients with observed difficulties at baseline (P

To access the results of this study, click here.

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