DALK with hydrops is safe and effective

Article

Deep anterior lamellar keratoplasty (DALK) is a safe and effective procedure in keratoconic eyes with previous hydrops.

Deep anterior lamellar keratoplasty (DALK) is a safe and effective procedure in keratoconic eyes with previous hydrops.

The retrospective, non-comparative study, led by Sheraz M Daya, Centre for Sight, East Grinstead, UK, involved 10 eyes of 10 patients. Each patient has previously receieved hydrops and underwent DALK.

DALK was completed using the Melles's technique of optical recognition with pre-Descemet's membrane dissection. The outcome measures included preoperative and postoperative uncorrected distance visual acuity and best spectacle corrected distance visual acuity (BSCVA), postoperative spherical equivalent (SEQ), keratometry and adverse events.

Preoperative BSCVA was 6/24 or worse in all eyes and at the last follow-up it was 6/12 or better in all eyes. Six eyes experienced intraoperative microperforation but penetrating keratoplasty conversion was not required.

The mean SEQ was −2.4±4.2 D, keratometric astigmatism was 3.8±1.6 D and refractive astigmatism was 3.4±2.2 D, whereas the mean postoperative keratometry was 43.7±2.6 and central pachymetry 572.6±65.0 µm.

The study can be found in the British Journal of Ophthalmology.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
João Pedro Marques, MD, MSc, PhD discusses a retrospective study of 800 patients with inherited retinal diseases during the American Society of Retina Specialists (ASRS) annual meeting
Christine Curcio, PhD, of the University of Alabama at Birmingham Heersink School of Medicine, shares histology update and revised nomenclature for OCT with Sheryl Stevenson of the Eye Care Network and Ophthalmology Times
© 2025 MJH Life Sciences

All rights reserved.