Cefazolin injection reduces the rate of postoperative endophthalmitis

July 5, 2012

Administering cezafolin injections after cataract surgery reduces the rate of postoperative endophthalmitis.

Administering cefazolin injections after cataract surgery reduces the rate of postoperative endophthalmitis, claims a study in the journal Bio Med Central.

Dr Pedro Romero-Aroca et al., Ophthalmology Service. Hospital Universitari Sant Joan, IISPV, Universidad Rovira i Virgili, Reus, Spain, conducted a prospective, observational study on 25001 patients.

All participants were divided into two groups: Group 1, consisting of 11696 patients, was operated on between January 2002 and December 2002 and Group 2, with 13305 patients, was administered a 1 mg/0.1 bolus of intracameral cefazolin between January 2003 and December 2009.

Of the patients studied, there were 76 cases of endophthalmitis in Group 1, compared to 7 in Group 2. Postoperative endophthalmitis rate decreased from 0.63% to 0.05% after a cefazolin. The relative risk of endophthalmitis in Group 1, compared to Group 2, was 11.45.

Intracameral bolus injections of cefazolin after cataract surgery significantly reduce the rate of postoperative endophthalmitis.