An assessment of neovascular AMD activity

Looking at an activity socring system to define lesions associated with wet AMD by quantifying their activity to determine the need for treatment.

Key Points


Activity scoring system

The proposed ASS is based on the well-known and widely used signs and findings of active CNV:

Apart from FA staining pattern, all of the other assessments are based on the changes in each parameter (same-baseline/increased/decreased) and given a number to define the activity. At the end of the assessment, the numbers are totalled and an activity score is obtained.

Activity scores (AS) can range between 0 and 14. We believe that a CNV lesion with AS of 6–7 or more requires treatment and <6 does not. We are currently compiling a paper to more accurately determine the cut off AS to separate those lesions that need treatment and those that do not.