Artificial tear preferences in post-LASIK patients

July 1, 2009

Examining how best to treat dry eye in LASIK patients.

Key Points

The answer, in my opinion, is not to avoid performing surgery on these patients but to treat them appropriately for dry eye during the postoperative period and, if necessary, preoperatively.

We screen for dry eye carefully, with a complete history designed to assess symptoms and environmental contributors to dryness, as well as to rule out other conditions that mimic dry eye. I find tear break-up time (<15 seconds) to be currently the most reliable objective measure of dry eye. I also look at Schirmer's, lissamine green staining, the quantity and quality of the tear lake and examine the lid margins carefully.

Dr Dan Durrie and I compared PRK to thin-flap LASIK in a contralateral eye study. The patients had no more complaints of dryness and discomfort in the LASIK eye than the PRK eye, nor could we find any difference in objective tear testing measures. Corneal sensation was also the same in both eyes. We concluded that corneal innervation is minimally disrupted with thinner flaps.

Still, dry eye should be managed proactively to ensure that the typically excellent vision experienced by LASIK patients is not compromised by dry eye symptoms. Postoperatively, artificial tears and cyclosporine therapy are both very effective in resolving symptoms.

We used to offer patients very limited guidance on artificial tear selection and use. Now we typically provide them with a high-quality tear with instructions to use it q.i.d. if they had preoperative dry eye symptoms and p.r.n. if they did not. Based on the results of a study I recently participated in, my artificial tear of choice is Blink Tears (Abbott Medical Optics). Its unique visco-adaptive formula, combined with its unique mechanism of action, helps the drop adhere to the cornea and maintain a thicker tear film for a longer period of time.

Tear comparison study

We conducted a randomized, open-label, multicenter contralateral eye study of 201 patients undergoing bilateral LASIK. Beginning one week after LASIK, patients were instructed to use Blink Tears in one eye and Optive (Allergan), Systane (Alcon), or Refresh Tears (Allergan) in the other eye for one month.

Patients overwhelmingly said LASIK improved their quality of life; that they were able to return to normal daily activities within one to three days; and that they would recommend the procedure to others. The vast majority (86%) said that artificial tears helped improve their dry eye symptoms.

This study reiterates not only the importance of proactively treating post-LASIK dry eye, but the difference that a high-quality, long-lasting, and non-blurring tear can make in overall patient satisfaction.