|Articles|November 1, 2008

When good blebs go bad: remodelling a filtering bleb

Bleb creation and modification should be viewed as any other construction project, according to Dr Andrew Iwach.

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Subscribe Now!

Latest CME

Video

Rapid Reviews in Retina™: Emerging Updates from Fall 2024 - Addressing the Wealth of New Data in Treatments for nAMD and DME

Diana V. Do, MD; Michael W. Stewart, MD; Paolo Lanzetta, MD; Dilraj Grewal, MD

Video

(CME Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

Rachel Simpson, MD; James Murphy, MD; Mary Qiu, MD; Jessica Steen, OD, FAAO

Video

(CME Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

David S. Liao, MD, PhD; Chang Sup Lee, MD; Douglas Matsunaga, MD; Daniel Su, MD

$(CME Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery$

Video

(CME Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery

Zeba A. Syed, MD

Video

(COPE Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

David S. Liao, MD, PhD; Chang Sup Lee, MD; Douglas Matsunaga, MD; Daniel Su, MD

Video

(COPE Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

Rachel Simpson, MD; James Murphy, MD; Mary Qiu, MD; Jessica Steen, OD, FAAO

Video

(CME Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

David M. Brown, MD, FACS; Dilraj S. Grewal, MD

Video

Navigating the Glaucoma Therapeutic and Surgical Landscape: From Conventional to Cutting-Edge

Deborah Ristvedt, DO; Melissa Tawa, OD, FAAO

Video

(CME Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

Melissa Barnett, OD, FAAO, FSLS, FBCLA; Cecelia Koetting, OD, FAAO, DipABO; Quan Đông Nguyễn, MD, MSc; Jennifer Li, MD

Video

(COPE Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

Melissa Barnett, OD, FAAO, FSLS, FBCLA; Cecelia Koetting, OD, FAAO, DipABO; Quan Đông Nguyễn, MD, MSc; Jennifer Li, MD

Video

(CME Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

Marjan Farid, MD; John Hovanesian, MD; Beeran Meghpara, MD

Video

(COPE Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

Marjan Farid, MD; John Hovanesian, MD; Beeran Meghpara, MD

Video

(CME Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

Nathan C. Steinle, MD

Video

(CME Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

David A. Eichenbaum, MD

Video

(CME Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

Tanner Ferguson, MD; Taj Nasser, MD, FWCRS

Video

(COPE Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

Nathan C. Steinle, MD

Video

(COPE Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

Tanner Ferguson, MD; Taj Nasser, MD, FWCRS

Video

(COPE Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

David A. Eichenbaum, MD

Video

(CME Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

Jacob Lang, OD, FAAO; Selina R. McGee, OD, FAAO; Neda Shamie, MD

Video

Neurotrophic Keratitis Insights: An Interactive Corneal Sensitivity Testing Workshop

John D. Gelles, OD, FAAO, FIAOMC, FCLSA, FSLS, FBCLA; John Hovanesian, MD, FACS

Video

(COPE Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

Jacob Lang, OD, FAAO; Selina R. McGee, OD, FAAO; Neda Shamie, MD

Video

(COPE Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

Arjan Hura, MD; Neda Shamie, MD; Kristin Barnes, OD

Video

(CME Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

Arjan Hura, MD; Neda Shamie, MD; Kristin Barnes, OD

Video

Rapid Reviews in Retina™: Emerging Updates from Spring 2025—Addressing the Wealth of New Data in Treatments for Neovascular Retinal Disease

SriniVas Sadda, MD, FARVO; Nathan Steinle, MD

Video

Interventional Dry Eye: A Stepwise Treatment & Management Approach

Mark Schaeffer, OD, FAAO; Mile Brujic, OD, FAAO; Nate Lighthizer, OD, FAAO, FAAOMS; Selina R. McGee, OD, FAAO

Video

(CME Track) Rapid Reviews in Retina™: Emerging Updates from Summer 2025—Addressing the Wealth of New Data in Treatments for Neovascular Retinal Disease

Mark R. Barakat, MD, FASRS; David Eichenbaum, MD, FASRS

Video

(CME Track) A Forward Look at Anti-VEGF Therapies: A Paradigm Shift in Neovascular Retinal Disease Management

David Almeida, MD, PhD, MBA; Margaret A. Chang, MD, MS; Arshad M. Khanani, MD, MA, FASRS; Jessica Randolph, MD

Video

(CME Track) Collaborating Across the Continuum™: Best Practices in Patient-Centric Team Management of XLRP

Ramiro Maldonado, MD; Rebecca Nelson, MS, CGC; Robert A. Sisk, MD, FACS, FASRS

Video

(CME Track) The Evolution of MacTel Management: Integrating Neuroprotective Therapies Into Clinical Practice

Dante Pieramici, MD, FASRS; Dean Eliott, MD; Robin A. Vora, MD; Charles C. Wykoff, MD, PhD, FASRS

Video

(CME Track) Community Collaborative Connections™: Optimizing the Collaborative Care of Neovascular Retinal Disease in a New Age of Treatment

Dilsher Dhoot, MD, FASRS; Jordana G. Fein, MD, MS; Deep Parikh, MD; Xiao-Yi (Ellie) Zhou, MD

Video

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

SriniVas R. Sadda, MD, FARVO; Mark R. Barakat, MD, FASRS; David A. Eichenbaum, MD, FASRS

Video

(CME Track) Beyond the Collarette: Empowering Patients in the Management of Demodex Blepharitis

Stephen C. Pflugfelder, MD; Cecelia Koetting, OD, FAAO, DipABO

Video

(COPE Track) Beyond the Collarette: Empowering Patients in the Management of Demodex Blepharitis

Stephen C. Pflugfelder, MD; Cecelia Koetting, OD, FAAO, DipABO

Video

Navigating Ocular Toxicities: A Multidisciplinary Roadmap for Managing Adverse Events in Targeted Cancer Therapy

Basil Williams, MD; Maura Di Nicola, MD

Multimedia

Expert Perspectives on Technological Advances in Cataract Surgery

Elizabeth Yeu, MD; Ashley Behrens, MD; Jade Coats, OD

Multimedia

Expanding Treatment Options for Demodex Blepharitis: Patient-Centric Approaches to Therapy

Jade Coats, OD, FAAO; Angela Y. Zhu, MD

Multimedia

Expanding Treatment Options for Demodex Blepharitis: Patient-Centric Approaches to Therapy

Jade Coats, OD, FAAO; Angela Y. Zhu, MD

Multimedia

(CME Credit) Community Practice Connections™: Applying Advances in Neovascular Retinal Disease - Expanding Treatment Intervals & Enhancing Outcomes

Arshad M. Khanani, MD, MA, FASRS; Carl J. Danzig, MD, FASRS; Jennifer I. Lim, MD, FARVO

Multimedia

Interventional Glaucoma Treatment: Evolving Paradigms for Addressing Unmet Needs

Deborah Ristvedt, DO; Melissa Tawa, OD, FAAO

Multimedia

Burst CME™ Part 3: Initiating Early Intervention in Patients With Glaucoma Who Fail Pharmacological Therapy

Deborah Ristvedt, DO; Melissa Tawa, OD, FAAO

Multimedia

(CME Track) Burst CME™ Part 1: Insights Into Glaucoma and the Need for Early Intervention

Deborah Ristvedt, DO; Melissa Tawa, OD, FAAO

Multimedia

Interventional Glaucoma Treatment: Evolving Paradigms for Addressing Unmet Needs

Deborah Ristvedt, DO; Melissa Tawa, OD, FAAO

In-Person Event

Beyond the Collarette: Empowering Patients in the Management of Demodex Blepharitis

December 4, 2025

Multimedia

(COPE Credit) Community Practice Connections™: Applying Advances in Neovascular Retinal Disease - Expanding Treatment Intervals & Enhancing Outcomes

Arshad M. Khanani, MD, MA, FASRS; Carl J. Danzig, MD, FASRS; Jennifer I. Lim, MD, FARVO

Multimedia

(CME Track) Neurotrophic Keratitis in Focus – From Early Recognition to Strategic Intervention

Jacqueline Theis, OD, FAAO; Cecelia Koetting, OD, FAAO, DipABO; Melissa Barnett, OD, FAAO, FSLS, FBCLA

Multimedia

(COPE Track) Neurotrophic Keratitis in Focus – From Early Recognition to Strategic Intervention

Jacqueline Theis, OD, FAAO; Cecelia Koetting, OD, FAAO, DipABO; Melissa Barnett, OD, FAAO, FSLS, FBCLA

Multimedia

(COPE Track) Leveraging Rho Kinase Inhibition in Glaucoma Management — How Can Novel Treatment Pathways Impact Patient Outcomes?

Mitch Ibach, OD, FAAO; Jessica Steen, OD, FAAO

Multimedia

(CME Track) Leveraging Rho Kinase Inhibition in Glaucoma Management — How Can Novel Treatment Pathways Impact Patient Outcomes?

Mitch Ibach, OD, FAAO; Jessica Steen, OD, FAAO

In-Person Event

EnVision Summit

February 13-16, 2026

Video

(CME Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

Laxmi V. Devisetty, MD; Rodney P. Coe, MD, MS; Majda Hadziahmetovic, MD; Xiao Yi (Ellie) Zhou, MD

Multimedia

(CME Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

Rahul Tonk, MD, MBA

Video

(CME Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

Adrienne W. Scott, MD, FASRS; Justine Cheng, MD; Hong-Uyen Hua, MD; Sherrol A. Reynolds OD, FAAO, FNAP

Video

(CME Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

Sara T. Wester, MD, FACS; Cecelia Koetting, OD; Sophie Liao, MD; Jennifer Murdock, MD

Video

Practical Approaches to Modern Dry Eye Treatment and Management

Marc R. Bloomenstein, OD, FAAO; Cory J. Lappin, OD, MS, FAAO; Selina R. McGee, OD, FAAO

Video

(COPE Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

Laxmi V. Devisetty, MD; Rodney P. Coe, MD, MS; Majda Hadziahmetovic, MD; Xiao Yi (Ellie) Zhou, MD

Video

(COPE Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

Sara T. Wester, MD, FACS; Cecelia Koetting, OD; Sophie Liao, MD; Jennifer Murdock, MD

$(COPE Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery$

Video

(COPE Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery

Zeba A. Syed, MD

Video

(COPE Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

Adrienne W. Scott, MD, FASRS; Justine Cheng, MD; Hong-Uyen Hua, MD; Sherrol A. Reynolds OD, FAAO, FNAP

Multimedia

(COPE Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

Rahul Tonk, MD, MBA

In-Person Event

20th Annual Controversies in Modern Eye Care

April 19, 2026

Video

(CME Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

Yasha Modi, MD; Carolyn Majcher, OD, FAAO, FORS

Video

(COPE Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

Yasha Modi, MD; Carolyn Majcher, OD, FAAO, FORS

Video

(COPE Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

David M. Brown, MD, FACS; Dilraj S. Grewal, MD

Video

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

Lejla Vajzovic, MD, FASRS; Ramiro Maldonado, MD

Video

(CME Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

Veeral Sheth, MD, MBA, FASRS, FACS; Mark R. Barakat, MD, FASRS; Geeta Lalwani, MD; Xiao Yi Zhou, MD

Video

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

Lejla Vajzovic, MD, FASRS; Ramiro Maldonado, MD

Video

(COPE Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

Veeral Sheth, MD, MBA, FASRS, FACS; Mark R. Barakat, MD, FASRS; Geeta Lalwani, MD; Xiao Yi Zhou, MD

Virtual Event

Collaborative Care Symposium

May 2-3, 2026

When good blebs go bad: remodelling a filtering bleb

Newsletter

Related Content

Efficiency in glaucoma practices begins with an intentional design

Ciliatech leadership comments on CE mark for novel glaucoma device

Feasibility of artificial intelligence in leading glaucoma care

Nicox and Kowa enter commercialisation agreement for NCX 470 glaucoma eye drop

Perfuse Therapeutics shares findings from glaucoma and diabetic retinopathy trials of PER-001

Latest CME

Rapid Reviews in Retina™: Emerging Updates from Fall 2024 - Addressing the Wealth of New Data in Treatments for nAMD and DME

(CME Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

(CME Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

(CME Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery

(COPE Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

(COPE Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

(CME Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

Navigating the Glaucoma Therapeutic and Surgical Landscape: From Conventional to Cutting-Edge

(CME Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

(COPE Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

(CME Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

(COPE Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

(CME Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

(CME Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

(CME Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

(COPE Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

(COPE Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

(COPE Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

(CME Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

Neurotrophic Keratitis Insights: An Interactive Corneal Sensitivity Testing Workshop

(COPE Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

(COPE Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

(CME Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

Rapid Reviews in Retina™: Emerging Updates from Spring 2025—Addressing the Wealth of New Data in Treatments for Neovascular Retinal Disease

Interventional Dry Eye: A Stepwise Treatment & Management Approach

(CME Track) Rapid Reviews in Retina™: Emerging Updates from Summer 2025—Addressing the Wealth of New Data in Treatments for Neovascular Retinal Disease

(CME Track) A Forward Look at Anti-VEGF Therapies: A Paradigm Shift in Neovascular Retinal Disease Management

(CME Track) Collaborating Across the Continuum™: Best Practices in Patient-Centric Team Management of XLRP

(CME Track) The Evolution of MacTel Management: Integrating Neuroprotective Therapies Into Clinical Practice

(CME Track) Community Collaborative Connections™: Optimizing the Collaborative Care of Neovascular Retinal Disease in a New Age of Treatment

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

(CME Track) Beyond the Collarette: Empowering Patients in the Management of Demodex Blepharitis

(COPE Track) Beyond the Collarette: Empowering Patients in the Management of Demodex Blepharitis

Navigating Ocular Toxicities: A Multidisciplinary Roadmap for Managing Adverse Events in Targeted Cancer Therapy

Expert Perspectives on Technological Advances in Cataract Surgery

Expanding Treatment Options for Demodex Blepharitis: Patient-Centric Approaches to Therapy

Expanding Treatment Options for Demodex Blepharitis: Patient-Centric Approaches to Therapy

(CME Credit) Community Practice Connections™: Applying Advances in Neovascular Retinal Disease - Expanding Treatment Intervals & Enhancing Outcomes

Interventional Glaucoma Treatment: Evolving Paradigms for Addressing Unmet Needs

Burst CME™ Part 3: Initiating Early Intervention in Patients With Glaucoma Who Fail Pharmacological Therapy

(CME Track) Burst CME™ Part 1: Insights Into Glaucoma and the Need for Early Intervention

Interventional Glaucoma Treatment: Evolving Paradigms for Addressing Unmet Needs

Beyond the Collarette: Empowering Patients in the Management of Demodex Blepharitis

(COPE Credit) Community Practice Connections™: Applying Advances in Neovascular Retinal Disease - Expanding Treatment Intervals & Enhancing Outcomes

(CME Track) Neurotrophic Keratitis in Focus – From Early Recognition to Strategic Intervention

(COPE Track) Neurotrophic Keratitis in Focus – From Early Recognition to Strategic Intervention

(COPE Track) Leveraging Rho Kinase Inhibition in Glaucoma Management — How Can Novel Treatment Pathways Impact Patient Outcomes?

(CME Track) Leveraging Rho Kinase Inhibition in Glaucoma Management — How Can Novel Treatment Pathways Impact Patient Outcomes?

EnVision Summit

(CME Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

(CME Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

(CME Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

(CME Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

Practical Approaches to Modern Dry Eye Treatment and Management

(COPE Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

(COPE Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

(COPE Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery

(COPE Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

(COPE Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

20th Annual Controversies in Modern Eye Care

(CME Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

(COPE Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

(COPE Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

(CME Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

(COPE Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

Collaborative Care Symposium