Operator-adjusted disc-definition is successful method of glaucoma detection

Article

A recent study featured in the Journal of Glaucoma claims that operator-adjusted disc-definition is ideal for glaucoma detection when using the RTVue-100 Fourier-domain optical coherence tomograph

A recent study featured in the Journal of Glaucoma claims that operator-adjusted disc-definition is ideal for glaucoma detection when using the RTVue-100 Fourier-domain optical coherence tomograph.

An investigation led by Professor Gábor Holló et al., Semmelweis University, Hungary, evaluated the repeatability and between-method differences of optic nerve head, retinal nerve fibre layer thickness (RNFLT) measurements with the RTVue-100 Fourier-domain OCT.

All 3 disc-definition functions were used on one eye of each 126 patients. This included 72 glaucomatous, 10 ocular hypertensive and 44 healthy control eyes. To calculate measurement repeatability 33 eyes were imaged 5 times.

The findings suggested that automatic disc-definition was significantly poorer than other methods. Repeatability was matched between manual and operator-adjusted methods in all but one parameter. Refractive error, disease category or peripapillary atrophy had no effect on repeatability. Parameters measured with manual and operator-adjusted methods demonstrated high intraclass correlation (93.5% to 99.9%).

Manual and operator-adjusted disc-definition functions have similar measurement repeatability and are not influenced by refractive error, glaucoma or parapapillary atrophy. It was reported that the RTVue-100 Fourier-domain OCT method is effective in the detection of glaucoma and has high intraclass correlation.

Newsletter

Join ophthalmologists across Europe—sign up for exclusive updates and innovations in surgical techniques and clinical care.

Recent Videos
SriniVas R. Sadda, MD, FARVO, shares key points from his retina presentation at the International SPECTRALIS Symposium
Robert Sergott, MD, describes fluorescence lifetime imaging ophthalmoscopy (FLIO) and the International SPECTRALIS Symposium – And Beyond (ISS) in Heidelberg, Germany.
Rayaz Malik, MBChB, PhD, a professor of medicine at Weill Cornell Medicine - Qatar, spoke with Ophthalmology Times Europe about his presentation. It's titled "An eye on neurodegenerative diseases: Challenging the dogma" at the International SPECTRALIS Sympsoium. In conversation with Hattie Hayes, Ophthalmology Times Europe
Anat Loewenstein, MD, describes her presentation on remote imaging for age-related macular degeneration and geographic atrophy at the International SPECTRALIS Symposium, in conversation with Hattie Hayes of Ophthalmology Times Europe
Tyson Brunstetter, OD, PhD, a US Navy Aerospace Optometrist at the NASA Johnson Space Center in Houston, Texas, shares key takeaways from his keynote at the International SPECTRALIS Symposium (ISS)
Rayaz Malik, MBChB, PhD, shares his presentation, titled An eye on neurodegenerative diseases: Challenging the dogma, at this year's International SPECTRALIS Symposium
At the Retina World Congress, Siegfried Priglinger, MD, speaks about ensuring the best outcomes for preschool-aged patients
At the 2025 ASCRS meeting, Robert Ang, MD said small aperture IOLs can benefit all patients, especially those with complex corneas or who have undergone previous corneal refractive surgery
Viha Vig, MBChB graduate student at the University of Auckland, New Zealand, discusses her poster presentation on the relationship between mitochondiral disease, Alzheimer disease, and other types of dementia.
Alfredo Sadun, MD, PhD, chief of Ophthalmology at the Doheny Eye Institute, University of California Los Angeles, shared exciting new research with the Eye Care Network during the Association for Research in Vision and Ophthalmology (ARVO) meeting on the subject of Leber hereditary optic neuropathy (LHON).
© 2025 MJH Life Sciences

All rights reserved.