Significant ophthalmological irregularities were discovered in children with Silver-Russell syndrome (SRS)
Significant ophthalmological irregularities were discovered in children with Silver-Russell syndrome (SRS), according to findings published in the British Journal of Ophthalmology.
A team led by Marita Andersson Grönlund, Department of Paediatric Ophthalmology, Sahlgrenska University Hospital, Gothenburg, Sweden, evaluated 18 children with SRS. Full-field electroretinogram, slit-lamp examination and ophthalmoscopy were used to record visual acuity (VA), refraction, strabismus, near point of convergence (NPC) and axial length measurements. Fundus photographs provided digitial image analysis. The findings were compared with a control group of children who matched the age and gender of the SRS patients.
Of the 18 children studied, 17 presented with ophthalmological abnormalities. Anisometropia was found in 3 children, refractive errors were found in 11 children, total axial length was reduced compared to the control group. Retinal vessel tortuosity increased in 4 children and small optic discs were discovered in 3 children.
The findings strongly recommend ophthalmic examinations in children with SRS.