Oblique parallel incisions in 25G surgery improves healing

Article

Performing 25-gauge pars plana vitrectomy with oblique parallel incisions rather than with standard straight incisions, may allow for more complete postoperative wound sealing.

Performing 25-gauge pars plana vitrectomy with oblique parallel incisions rather than with standard straight incisions, may allow for more complete postoperative wound sealing, according to a report published in the September issue of Graefe's Archive for Clinical and Experimental Ophthalmology.

Stanislao Rizzo and colleagues from the Santa Chiara Hospital, Pisa, Italy enrolled 45 patients with macular holes. In 15 eyes, operations were carried out using oblique parallel insertion, in a further 15, oblique perpendicular insertions were used, and the remaining 15 received straight incisions (SI). Each patient underwent ultrasound biomicroscopy (UBM) examinations, one day, one week and one month postoperatively.

Oblique parallel insertions healed immediately following removal of the 25-gauge cannula. At one day postoperatively, all sclerotomies were well-healed with the internal wound lips showing excellent apposition. In addition, 39 sclerotomies were undetectable by UBM and six were only just observable.

In the oblique perpendicular insertion group, the incisions also healed immediately and all sclerotomies were well-healed by one day postoperatively. However, minimal gape was visible on UBM. Three eyes also showed peripheral cilio-choroidal detachment at one day postoperatively — this was resolved in all cases by seven days follow-up.

In the straight incision group, 10 cases of conjunctival blebs developed. Of these, seven required air-gas refilling and three required suturing of the sclerotomies. By one day postoperatively, five subjects developed hypotony and UBM demonstrated significant gaps in all sites.

The authors concluded that oblique parallel incisions allow for better postoperative wound sealing.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
João Pedro Marques, MD, MSc, PhD discusses a retrospective study of 800 patients with inherited retinal diseases during the American Society of Retina Specialists (ASRS) annual meeting
Christine Curcio, PhD, of the University of Alabama at Birmingham Heersink School of Medicine, shares histology update and revised nomenclature for OCT with Sheryl Stevenson of the Eye Care Network and Ophthalmology Times
© 2025 MJH Life Sciences

All rights reserved.