ICGA correlate with OCT findings for polypodal lesions

November 29, 2012

Indocyanine green angiography (ICGA) correlate with OCT findings of polypoidal lesions in polypoidal choroidal vasculopathy.

Indocyanine green angiography (ICGA) correlate with OCT findings of polypoidal lesions in polypoidal choroidal vasculopathy, claims a study in the journal Retina.

An investigation led by Dr C. Ueno Department of Ophthalmology, Graduate School of Medicine, Osaka University, Osaka, Japan, involved 51 eyes of 51 patients with treatment-naive polypoidal choroidal vasculopathy. Each subject was administered intravitreal ranibizumab injections. Changes in polypoidal lesions on ICGA and OCT and their correlation over three months were recorded. Ranibizumab was injected again, determined by the presence of residual fluid on OCT.

ICGA detected 75 polypoidal lesions and all OCT lesions demonstrated baseline protrusion of the retinal pigment epithelium. Of the lesions, 49 persisted on ICGA, retinal pigment epithelium protrusion resolved in two lesions, decreased in four lesions, were stable in 36 lesions and increased in seven lesions.

It was discovered that polypoidal lesions persisted more often on OCT, even though ICGA and OCT presented with the same efficacy for ranibizumab.

To view the abstract click here.