High pulse pressure linked to OAG

Article

High-tension open angle glaucoma (htOAG) is associated with high pulse pressure, increased carotid arterial stiffness and, in people treated for systemic hypertension, low diastolic perfusion pressure.

High-tension open angle glaucoma (htOAG) is associated with high pulse pressure, increased carotid arterial stiffness and, in people treated for systemic hypertension, low diastolic perfusion pressure, according to a report published in the June issue of Archives of Ophthalmology.

Caroline Hulsman and colleagues from The Netherlands Institute for Neuroscience conducted a study to investigate cross-sectional associations among blood pressures (BPs), arterial stiffness and open angle glaucoma (OAG). Participants were recruited from the population-based Rotterdam Study. Subjects were classified as either htOAG or normal tension OAG (ntOAG), according to an intraocular pressure (IOP) of greater than, or less than 21 mmHg. Pulse pressure was defined as the difference between systolic and diastolic BP, while diastolic perfusion pressure was defined as the difference between diastolic BP and IOP.

A total of 5,317 subjects were included in the study. In subjects with higher pulse pressure, the prevalence of htOAG was elevated. In those who were treated for systemic hypertension, low diastolic perfusion pressure (<50 mmHg) was inversely associated with ntOAG and positively associated with htOAG.

It was concluded that htOAG is particularly associated with high pulse pressure.

Recent Videos
(Image credit: Ophthalmology Times Europe) AGS 2025: Clemens Strohmaier, PhD, on improving aqueous humour outflow following excimer laser trabeculostomy
Anat Loewenstein, MD, speaks about the 22nd Annual Angiogenesis, Exudation, and Degeneration Meeting in February 2025 and shares her global forecast for AI-driven home OCT
Sarah M. Thomasy, DVM, PhD, DACVO, a veterinary ophthalmologist at UC Davis, talks about how her research at the Glaucoma 360 symposium
I. Paul Singh, MD, an anterior segment and glaucoma specialist, discusses the Glaucoma 360 conference, where he participated in a panel discussion on the use of artificial intelligence (AI) in glaucoma care.
Charles Wykoff, MD, PhD, discusses his Floretina ICOOR presentation topic, retinal non-perfusion in diabetic retinopathy, with David Hutton, editor of Ophthalmology Times
Elizabeth Cohen, MD, discusses the Zoster Eye Disease study at the 2024 AAO meeting
Vikas Chopra at AAO 2024: Advancements in MIGS are transforming patient care
Victoria L Tseng, MD, PhD, professor of ophthalmology and glaucoma specialist, UCLA
© 2025 MJH Life Sciences

All rights reserved.