Glaucoma gene discovery by UI researchers

Article

The gene sFRPI plays a key role in glaucoma development, and researchers from the University of Iowa (UI) have found that an over-expression of the gene raises fluid pressure in the eyes.

Iowa City, IA-The gene sFRPI plays a key role in glaucoma development, and researchers from the University of Iowa (UI) have found that an over-expression of the gene raises fluid pressure in the eyes.

The effects of excess sFRP1 protein were tested on mice and human donor eyes by researchers. They discovered that when there was an abnormality, the resulting proteins interfered with a singular pathway.

According to John Fingert, MD, PhD, a UI assistant professor of ophthalmology, the discovery could eventually facilitate early diagnosis and treatment of glaucoma.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Jeremiah Tao, MD, FACS, discusses his Egyptian Ophthalmological Society keynote, which focused on risk management and avoiding surgical complications in oculofacial surgery
Omer Trivizki, MD, MBA, a retina specialist from Tel Aviv Medical Center, speaks about VOY-101, a Novel, Complement-Modulating Gene Therapy for Geographic Atrophy at the American Society of Retina Specialists (ASRS) Annual Meeting
João Pedro Marques, MD, MSc, PhD discusses a retrospective study of 800 patients with inherited retinal diseases during the American Society of Retina Specialists (ASRS) annual meeting
© 2025 MJH Life Sciences

All rights reserved.