Combigan more cost-effective than Cosopt

Article

The fixed combination of brimonidine/timolol is more cost effective than dorzolamide/timolol, according to a study published in the September/October issue of the European Journal of Ophthalmology.

The fixed combination of brimonidine/timolol (Combigan;Allergan) is more cost effective than dorzolamide/timolol (Cosopt; Merck), according to a study published in the September/October issue of the European Journal of Ophthalmology.

A. Hommer, of the Krankenanstalt Sanatorium, Vienna, Austria, and colleagues conducted a review of the literature concerning the efficacy, tolerability and cost implications (across several European countries) of various IOP-lowering therapies administered for a three-month period.

The researchers determined equal efficacy of brimonidine 0.2% and dorzolamide 2% as either fixed combinations with or as adjunctives to timolol 0.5% therapy. At three and 12 months, however, the brominidine/timolol fixed combination proved to be the least costly option. Brimonidine as an adjunct to timolol was a more expensive alternative than the fixed combination, and dorzolamide as an adjunct to timolol represented a still more expensive option.

The team concluded that, as the efficacy was equal but the cost was lower, the brominidine/timolol fixed combination offered the greatest cost effectiveness in all countries studied of the IOP-lowering therapies reviewed.

Newsletter

Get the essential updates shaping the future of pharma manufacturing and compliance—subscribe today to Pharmaceutical Technology and never miss a breakthrough.

Recent Videos
Harvey Uy, MD, DPBO, FVRSP, speaks about artificial intelligence (AI) and optical coherence tomography (OCT) at the 2025 European Society of Retina Specialists (EURETINA) Congress.
EURETINA 2025: Boris Stanzel, MD, methotrexate is rocking the European retina landscape
Jeremiah Tao, MD, FACS, discusses his Egyptian Ophthalmological Society keynote, which focused on risk management and avoiding surgical complications in oculofacial surgery
© 2025 MJH Life Sciences

All rights reserved.