Cell loss the same with standard phaco and MICS

Article

Phacoemulsification performed with a standard technique yields no significant differences in endothelial cell loss or endothelial morphology when compared with the procedure performed by bimanual microincision cataract surgery (MICS), according to the results of a study published in the August issue of the Journal of Cataract and Refractive Surgery.

Phacoemulsification performed with a standard technique yields no significant differences in endothelial cell loss or endothelial morphology when compared with the procedure performed by bimanual microincision cataract surgery (MICS), according to the results of a study published in the August issue of the Journal of Cataract and Refractive Surgery.

Rita Mencucci, MD and co-workers from the Department of Oto-Neuro-Ophthalmological Surgical Sciences Eye Clinic, University of Florence, Florence, Italy, randomized 80 patients into two groups; 40 eyes to undergo standard stop and chop phaco and the other 40 eyes to receive stop and chop phaco with bimanual MICS. Corneal endothelial cell counts, coefficient of variation in cell size, hexagonality and pachymetry were assessed preoperatively and then again one and three months postoperatively.

Preoperatively, the mean cell count for the entire sample was 2,245 cells/mm² ± 37 (SE). The mean count decreased by 102 cells at one month and by 144 at three months. The difference between the standard group and the MICS group was 25 cells at baseline, 19 cells at one month and 19 cells at three months. There were no changes in the coefficient of variation or morphology in the overall sample and the pattern of change did not differ between the two groups. Corneal thickness increased by 10.2 µm in the overall sample and approached baseline values by three months with an increase of 3.4 µm. There was no difference in corneal thickness between the two groups.

The authors concluded that no significant differences could be found in corneal endothelial cell loss or endothelial morphology between the two techniques.

Newsletter

Join ophthalmologists across Europe—sign up for exclusive updates and innovations in surgical techniques and clinical care.

Recent Videos
Christine Curcio, PhD, of the University of Alabama at Birmingham Heersink School of Medicine, shares histology update and revised nomenclature for OCT with Sheryl Stevenson of the Eye Care Network and Ophthalmology Times
SriniVas R. Sadda, MD, FARVO, shares key points from his retina presentation at the International SPECTRALIS Symposium
Robert Sergott, MD, describes fluorescence lifetime imaging ophthalmoscopy (FLIO) and the International SPECTRALIS Symposium – And Beyond (ISS) in Heidelberg, Germany.
Rayaz Malik, MBChB, PhD, a professor of medicine at Weill Cornell Medicine - Qatar, spoke with Ophthalmology Times Europe about his presentation. It's titled "An eye on neurodegenerative diseases: Challenging the dogma" at the International SPECTRALIS Sympsoium. In conversation with Hattie Hayes, Ophthalmology Times Europe
Anat Loewenstein, MD, describes her presentation on remote imaging for age-related macular degeneration and geographic atrophy at the International SPECTRALIS Symposium, in conversation with Hattie Hayes of Ophthalmology Times Europe
Tyson Brunstetter, OD, PhD, a US Navy Aerospace Optometrist at the NASA Johnson Space Center in Houston, Texas, shares key takeaways from his keynote at the International SPECTRALIS Symposium (ISS)
Rayaz Malik, MBChB, PhD, shares his presentation, titled An eye on neurodegenerative diseases: Challenging the dogma, at this year's International SPECTRALIS Symposium
At the Retina World Congress, Siegfried Priglinger, MD, speaks about ensuring the best outcomes for preschool-aged patients
At the 2025 ASCRS meeting, Robert Ang, MD said small aperture IOLs can benefit all patients, especially those with complex corneas or who have undergone previous corneal refractive surgery
Related Content
© 2025 MJH Life Sciences

All rights reserved.