Assessment of post-op IOL optic changes with AS-OCT

Methods and results

IOLs explanted because of different complications and sent to the Intermountain Ocular Research Center at the John A. Moran Eye Center, University of Utah were used. These included the following:

Gross and light microscopy of the single-piece hydrophobic acrylic lenses in the dry state showed no optic opacification and absence of glistenings within their optics. The corresponding AS-OCT scans only showed the overall outline of the surfaces of the lenses. Removal of the lenses from warm solution and analysis at room temperature caused formation of intraoptic glistenings, which was confirmed under light microscopy. Corresponding ASOCT scans showed that the glistenings were overall homogeneously distributed within the entire optic, but sometimes absent in a small subsurface area.

Gross examination of the cadaver eyes from the MiyakeApple view revealed the presence of single-piece hydrophilic acrylic lenses implanted in the capsular bag, exhibiting overall a clear optic. ASOCT scans of the lenses, obtained before and after explantation from the cadaver eyes showed their overall outline, confirming the absence of any intraoptic changes. The ASOCT outline of these lenses appeared thinner and less bright than in the cases with calcification.