Assessment of post-op IOL optic changes with AS-OCT


Advantages found for location and density of intraoptic changes

Methods and results

IOLs explanted because of different complications and sent to the Intermountain Ocular Research Center at the John A. Moran Eye Center, University of Utah were used. These included the following:

Gross and light microscopy of the single-piece hydrophobic acrylic lenses in the dry state showed no optic opacification and absence of glistenings within their optics. The corresponding AS-OCT scans only showed the overall outline of the surfaces of the lenses. Removal of the lenses from warm solution and analysis at room temperature caused formation of intraoptic glistenings, which was confirmed under light microscopy. Corresponding ASOCT scans showed that the glistenings were overall homogeneously distributed within the entire optic, but sometimes absent in a small subsurface area.

Gross examination of the cadaver eyes from the MiyakeApple view revealed the presence of single-piece hydrophilic acrylic lenses implanted in the capsular bag, exhibiting overall a clear optic. ASOCT scans of the lenses, obtained before and after explantation from the cadaver eyes showed their overall outline, confirming the absence of any intraoptic changes. The ASOCT outline of these lenses appeared thinner and less bright than in the cases with calcification.

Related Videos
ARVO 2024: Andrew D. Pucker, OD, PhD on measuring meibomian gland morphology with increased accuracy
 Allen Ho, MD, presented a paper on the 12 month results of a mutation agnostic optogenetic programme for patients with severe vision loss from retinitis pigmentosa
Noel Brennan, MScOptom, PhD, a clinical research fellow at Johnson and Johnson
ARVO 2024: President-elect SriniVas Sadda, MD, speaks with David Hutton of Ophthalmology Times
Elias Kahan, MD, a clinical research fellow and incoming PGY1 resident at NYU
Neda Gioia, OD, sat down to discuss a poster from this year's ARVO meeting held in Seattle, Washington
Eric Donnenfeld, MD, a corneal, cataract and refractive surgeon at Ophthalmic Consultants of Connecticut, discusses his ARVO presentation with Ophthalmology Times
John D Sheppard, MD, MSc, FACs, speaks with David Hutton of Ophthalmology Times
Paul Kayne, PhD, on assessing melanocortin receptors in the ocular space
Osamah Saeedi, MD, MS, at ARVO 2024
© 2024 MJH Life Sciences

All rights reserved.